Background and aim: International Consensus guideline 2012 for the management of IPMN
and MCN of the pancreas was published, in which strategy of follow-up in branch duct
IPMN (BD-IPMN) was shown. We evaluated risk factor of invasive carcinoma (IC) in followed
BD-IPMN. Patients & Methods: Total 322 BD-IPMN cases were enrolled (age 68.0 years
old, gender male/female: 148/174, follow-up time: 1925 days). We divided this subject into
3 groups by imaging findings along IPMN guideline, "high risk stigmata" (HRS), "worrisome
features" (WF), and other cases except for HRS and WF (EHW). We retrospectively compared
with characteristics, ratio of imaging progression factor, and ratio of appearance of IC between
3 groups and evaluated risk factor for appearance of IC. Results: 1) HRS was 16, WF was
77, and EHW was 229. Ratio that location of IPMN was pancreas head (Ph) was 75.0%

