Abstract
Background: Incidence and prevalence of stroke is increasing in recent years, but diagnosis and management can be difficult because of the diversity of underlying risk factors and the absence of a uniform treatment approach. Aim of work:To study the admission and outcome of stroke in children in Sohag university Hospital Patients and methods: This observational, prospective cohort study was done at Pediatric department, Sohag University Hospitals in the period from 1/9/2009 to 31/8/2010. Patient having acute cerebrovascular stroke age between one month and 12years old were included. In addition to full history and systemic clinical examination, all patients have complete blood count, prothrombin time and partial thromboplastin times, echocardiography and brain computed tomography. Results: During the period of study 18 patients with acute stroke completed the study. The median age at onset was 1.5 months. We found that 12 patients (66.6%) have hemorrhagic strokes and 6 patients (33.4%) have ischemic stroke (P = 0.04). Among 12 patients who suffered from acute hemorrhagic stroke we observed that 10 patients (83 %) had no past history of vitamin K administration. Abnormalities in blood count and coagulation profile are more significantly common in patients with acute hemorrhagic stroke (P <0.001). Echocardiography was normal in all studied patients. Intraventricular hemorrhage was the main CT finding in acute hemorrhagic strokes whereas left cerebral infarction was the main finding in acute ischemic stroke. The overall mortality was 50 %. 2 (all males) patients (11 %) had complete recovery. Concerning disability, 7 patients (2 males) patients (39 %) had disability (5 patients of them had acute hemorrhagic stroke). Conclusions: Acute cerebrovascular stroke is relatively rare in our locality. Hemorrhagic stroke are more common than acute ischemic stroke. This could caused by lack of vitamin K administration. [ Int. J. Ch. Neuropsychiatry, 2012, 9(1&2):63-73]