Prolactinomas and nonfunctioning adenomas are the most common types of pituitary tumors. They may present initially with symptoms of endocrine dysfunction such as infertility, decreased libido, and galactorrhea, or with neurologic symptoms such as headache and visual changes. The diagnosis may also be made incidentally; the so called pituitary incidentaloma. Oversecretion of hormones from a dysfunctional pituitary tumor may result in classic clinical syndromes, the most common of which are hyperprolactinemia, acromegaly, and Cushing disease. In the diagnostic approach to a suspected pituitary tumor, it is important to evaluate complete pituitary function, because hypopituitarism is common. Therapy for pituitary tumors depends on the specific type, and should be managed with a team approach to include endocrinology and neurosurgery