Epilepsy co morbidites
Most cases of epilepsy begin in childhood → time that is essential to development of basic cognitive skills
* Uncontrolled seizures impair cognitive functions with effects being most sever in infancy & early childhood → need for early aggressive treatment & siezure control in those pts
* Deficits in cognition are identified by epileptics & their familes as a significant and one of the most important comorbidities
- As for the diagnosis of cognitive impairment at epilepsy
onset, it is not sufficient to ask the patients, because they
tend to underreport problems, which become evident with
testing. -
-Patients with epilepsy frequently report some subjective impairment in cognitive functioning, with prevalence rates ranging from 44% for difficulties in learning and psychomotor retardation to 59% for sleepiness or tiredness. In addition, 63% of patients perceive that AEDs prevent them from achieving activities or goals.
-Epilepsy Res. 68(1), 63–67 (2006).
-CNS Drugs 23(2), 121–137 (2009).
Attention & Concentration deficits
- Selective attention,concentration,focus attention are important for proper many tasks of life
- Deficits in attention are common in epilepsy and may affect other aspects of cognition
→ more with frontal epilepsies (attention)
→ more with complex partial seisure (sustained conc.)
→ more with children & younger pts
- In a study published in J of seisure 1992, found that 30 % of newly diagnosed adults with epilepsy with no brain lesions had deficits in sustained attention and mental flexibilty
- ↑ risk of ADHD with range from 17-58%
( pediat Neurol,2005,32-1-10,Child Neurol,2006,45,50-54 )
-
Attention & Concentration deficits
- Selective attention,concentration,focus attention are important for proper many tasks of life
- Deficits in attention are common in epilepsy and may affect other aspects of cognition
→ more with frontal epilepsies (attention)
→ more with complex partial seisure (sustained conc.)
→ more with children & younger pts
- In a study published in J of seisure 1992, found that 30 % of newly diagnosed adults with epilepsy with no brain lesions had deficits in sustained attention and mental flexibilty
- ↑ risk of ADHD with range from 17-58%
-
Attention & Concentration deficits
- Selective attention,concentration,focus attention are important for proper many tasks of life
- Deficits in attention are common in epilepsy and may affect other aspects of cognition
→ more with frontal epilepsies (attention)
→ more with complex partial seisure (sustained conc.)
→ more with children & younger pts
- In a study published in J of seisure 1992, found that 30 % of newly diagnosed adults with epilepsy with no brain lesions had deficits in sustained attention and mental flexibilty
- ↑ risk of ADHD with range from 17-58%
( pediat Neurol,2005,32-1-10,Child Neurol,2006,45,50-54 )
Attention & Concentration deficits
- Selective attention,concentration,focus attention are important for proper many tasks of life
- Deficits in attention are common in epilepsy and may affect other aspects of cognition
→ more with frontal epilepsies (attention)
→ more with complex partial seisure (sustained conc.)
→ more with children & younger pts
- In a study published in J of seisure 1992, found that 30 % of newly diagnosed adults with epilepsy with no brain lesions had deficits in sustained attention and mental flexibilty
- ↑ risk of ADHD with range from 17-58%