Elsayed Mohammed Abdelkreem Abdalla (MD, PhD)

Department of Pediatrics, Faculty of Medicine, Sohag University,
Nasser city, Sohag 82524, Egypt.
(002) 01114232126
d.elsayedmohammed@med.sohag.edu.eg
d.elsayedmohammed@yahoo.com

Lecturer of Pediatrics at the Faculty of Medicine, Sohag University with a solid medical, research, and teaching experience. Main domains are Pediatric emergencies, critical care, and inherited metabolic diseases. I am interested in developing a career which combines teaching and research, while maintaining my interest in clinical work.

EDUCATION

2013- 2018         Doctoral Degree of Pediatrics         Faculty of Medicine, Sohag University (Egypt)

2009-2013          Master of Pediatrics                        Faculty of Medicine, Sohag University

2000-2007          Bachelor of Medicine & surgery    Faculty of Medicine, Sohag University

EMPLOYMENT

Apr 2018-Present         Lecturer (Pediatrics)                    Faculty of Medicine, Sohag University

Aug 2013-Apr 2018     Assistant Lecturer (Pediatrics)     Faculty of Medicine, Sohag University

Apr 2012-Aug 2013     Demonstrator (Pediatrics)            Faculty of Medicine, Sohag University

Mar 2009-Apr 2012     Resident Physician (Pediatrics)   Sohag University Hospital

Mar 2008-Feb 2009      House officer                               Sohag University Hospital

RESEARCH EXPERIENCE

Jul 2015-Jul 2017               Department of Pediatrics, Gifu University (Japan)
 Working as a member of Professor Toshiyuki Fukao research group in the field of clinical and molecular characterization of inherited metabolic diseases, particularly disorders of ketone body metabolism.

Mar 2009-Aug 2012          Department of Pediatrics, Sohag University
Working on my master thesis entitled Clinical Features of Cerebral Cortex Malformation in Children: Observational Retrospective Study in Sohag University Hospital

SCHOLARSHIPS

Jul 2015-Jul 2017
Research scholarship from the Egyptian Government to perform my doctoral thesis at the Department of pediatrics, Gifu University (Japan).

TEACHING/ADMINISTRATIVE EXPERIENCE

Apr 2018-Present            Lecturer (Pediatrics), Sohag University

Apr 2012-Apr 2018         Demonstrator/Assistant Lecturer (Pediatrics), Sohag University

Dec 2017-Present             Member of Curriculum Reform Committee, Sohag Faculty of Medicine

Aug 2014-Jul 2015          Vice Director of International Students Unit, Sohag Faculty of Medicine

Feb 2014-Jul 2015           Member of Infection Control Unit, Sohag University Hospital

Sep 2013-Aug 2014          Vice Director of Student Assessment Unit, Sohag Faculty of Medicine

PROFESSIONAL MEDICAL EXPERIENCE

Apr 2018-Present             Consultant (Pediatrics&Neonatology), Sohag University Hospital

Apr 2012-Apr 2018          Specialist (Pediatrics&Neonatology), Sohag University Hospital

Jul 2015-Jul 2017             Visiting Physician, Gifu University (Japan)

Mar 2009-Apr 2012          Resident Physician (Pediatrics&Neonatology), Sohag University Hospital

MEMBERSHIPS

-Member of Egyptian Society of Medical Education (ESME)
-Member of Egyptian Society of Pediatric Intensive Care (ESPEC)

List of publications and conference presentations
PUBLICATIONS                orcid.org/0000-0002-8976-2989

Nakama M, Otsuka H, Ago Y, Sasai H, Abdelkreem E, Aoyama Y, Fukao T (2018) Intronic antisense Alu elements have a negative splicing effect on the inclusion of adjacent downstream exons. Gene 664:84-89. DOI: 10.1016/j.gene.2018.04.064

Sasai H, Aoyama Y, Otsuka H, Abdelkreem E, Naiki Y, Kubota M, Sekine Y, Itoh M, Nakama M, Ohnishi H, Fujiki R, Ohara O, Fukao T (2017) Heterozygous carriers of succinyl-CoA:3-oxoacid CoA transferase deficiency can develop severe ketoacidosis. J Inherit Metab Dis 40(6): 845–852. DOI: 10.1007/s10545-017-0065-z1

Aoyama Y, Sasai H, Abdelkreem E, Otsuka H, Nakama M, Kumar S, Aroor S, Shukla A, Fukao T (2017) A novel mutation (c.121-13T>A) in the polypyrimidine tract of the splice acceptor site of intron 2 causes exon 3 skipping in mitochondrial acetoacetyl-CoA thiolase gene. Mol Med Rep. 15(6): 3879-3884. DOI: 10.3892/mmr.2017.6434

Nguyen KN, Abdelkreem E, Colombo R, Hasegawa Y, Can NT, Bui TP, Le HT, Tran MT, Nguyen HT, Trinh HT, Aoyama Y, Sasai H, Yamaguchi S, Fukao T, Vu DC (2017) Characterization and outcome of 41 patients with beta-ketothiolase deficiency: 10 years' experience of a medical center in northern Vietnam. J Inherit Metab Dis 40(3): 395-401. DOI: 10.1007/s10545-017-0026-6

Sasai H, Aoyama Y, Otsuka H, Abdelkreem E, Nakama M, Hori T, Ohnishi H, Turner L, Fukao T (2017) A single nucleotide substitution T to A in the poly-pyrimidine stretch at splice acceptor site of intron 9 causes exon 10 skipping in ACAT1 gene. Mol Genet Genomic Med 5(2): 177-184. DOI: 10.1002/mgg3.275

Abdelkreema E, Alobaidy H, Aoyama Y, Mahmoud S, Abd El Aal M, Fukao T (2017) Two Libyan siblings with beta-ketothiolase deficiency: A case report and review of literature. Egypt J Med Hum Genet 18(2): 199-203. DOI: 10.1016/j.ejmhg.2016.11.001

Abdelkreem E, Akella RR, Dave U, Sane S, Otsuka H, Sasai H, Aoyama Y, Nakama M, Ohnishi H, Mahmoud S, Abd El Aal M, Fukao T (2017) Clinical and Mutational Characterizations of Ten Indian Patients with Beta-Ketothiolase Deficiency. In: Morava E., Baumgartner M., Patterson M., Rahman S., Zschocke J., Peters V. (eds) JIMD Reports, vol 35. Springer, Berlin, Heidelberg. DOI: 10.1007/8904_2016_26

Otsuka H, Sasai H, Abdelkreem E, Kawamoto N, Kawamoto M, Kamiya T, Tanimoto Y, Kikuchi A, Kure S, Numakura C, Hayasaka K, Fukao T (2016) Effectiveness of Medium-Chain Triglyceride Oil Therapy in Two Japanese Citrin-Deficient Siblings: Evaluation Using Oral Glucose Tolerance Tests. Tohoku J Exp Med. 240(4):323-328. DOI: 10.1620/tjem.240.323

Otsuka H, Sasai H, Nakama M, Aoyama Y, Abdelkreem E, Ohnishi H, Konstantopoulou V, Sass JO, Fukao T (2016) Exon 10 skipping in ACAT1 caused by a novel c.949G>A mutation located at an exonic splice enhancer site. Mol Med Rep. 14(5): 4906-4910. DOI: 10.3892/mmr.2016.5819

Erdol S, Ture M, Yakut T, Saglam H, Sasai H, Abdelkreem E, Otsuka H, Fukao T (2016) A Turkish patient with succinyl-CoA:3-oxoacid CoA transferase deficiency mimicking diabetic ketoacidosis. J Inborn Errors Metab Screen. 4(1): 1-5. DOI: 10.1177/2326409816651281

Abdelkreem E, Otsuka H, Sasai H, Aoyama Y, Hori T, Abd El Aal M, Mahmoud S, Fukao T (2016) Beta-ketothiolase deficiency: Resolving challenges in diagnosis. J Inborn Errors Metab Screen. 4(1): 1-9. DOI: 10.1177/2326409816636644

Sadek AA, Ahmed Sharaf AE, Abdelkreem EM, Abdul Wahed SR (2013) Clinical Features of Cerebral Cortex Malformations in Children: A Study in Upper Egypt. OMICS J Radiology. 2(5): 123. DOI: 10.4172/2167-7964.1000123

CONFERENCE PRESENTATIONS

Non-diabetic Ketoacidosis (oral presentation). 2nd Joint Al-Azhar Pediatric Conference, 05-07 Jul 2018, Alexandria, Egypt.

Clinical, biochemical, and molecular features of beta-ketothiolase deficiency: a case series of 23 patients (oral presentation). 4th Scientific Conference of Young Researchers, 17-18 Apr 2018, Sohag, Egypt.

Pediatric emergencies: case scenarios and pitfalls (oral presentation). 1st workshop of Sohag University Hospital PICU, 11 Apr 2018, Sohag Egypt.

Metabolism and disorders of ketone bodies (oral presentation). 1st Sohag Conference of Inborn Errors of Metabolism, 26-27 Feb 2018, Sohag Egypt.

Modes and settings of Mechanical Ventilation (oral presentation). Basics of Neonatal Mechanical Ventilation Workshop, 19-21 Jul 2017, Sohag, Egypt.

Clinical and mutational characterizations of 10 Indian patients with beta-ketothiolase deficiency (oral presentation). Conference of Japanese Society of Inherited Metabolic Diseases (JSIMD 58) 27-29 Oct 2016, Tokyo, Japan.

Molecular characterization of beta-ketothiolase deficiency in 10 Indians: Discovery of 4 novel mutations in ACAT1 gene (oral presentation). The 13th International Congress of Human Genetics (ICGH), 3-7 Apr 2016, Kyoto, Japan.

Pediatric emergencies; Case presentations (oral presentation). Pediatric Emergencies Workshop. 10-11 Jun 2015, Sohag, Egypt.

Pediatric Basic Life Support (oral presentation). 1st Aid Management Workshop. Medical Education and Development Center, Clinical Skill Lab, 1-9 Feb 2014, Sohag, Egypt.

OTHER SKILLS

Journal reviewing/editorial experience            publons.com/a/1391366/
A current reviewer at: Clinical Medicine Insights: Pediatrics (5 reviews)
                                    Oman Medical Journal (9 reviews)
A current editorial board member at:  BOAJ Pediatrics

IT
 International Computer Driving License (ICDL)
 Experience and daily use of Microsoft Office Suite.
 Experience in statistical analysis using SPSS program

Languages
 Arabic (native)
 English (very good) TOEFL iBT (102) on 5th May 2018
 Advanced English Conversation Course (Sohag University) with Excellent Grade (96%).

FURTHER INFORMATION
Date and place of birth: November 27th, 1984, Egypt
Nationality: Egyptian
Marital status: Married and have two daughters
Hobbies: Reading, running.
Charity/volunteering works

Attended conferences and workshops

CONFERENCES

 9th Scientific Congress of Pediatric Intensive Care. 19-20 Jul 2018, Cairo, Egypt.
 2nd Joint Al-Azhar Pediatric Conference. 05-07 Jul 2018, Alexandria, Egypt.
 4th Scientific Conference of Young Researchers. 17-18 Apr 2018, Sohag, Egypt.
 1st Sohag Conference of Inborn Errors of Metabolism. 26-27 Feb 2018, Sohag, Egypt.
 15th Annual Scientific Conference of Pediatric Department, Assiut University (Update on Diagnostic Spectra of Pediatrics). 7-10 Feb 2018, Luxor, Egypt.
 The Egyptian Society of Nephrology and Transplantation (ESNT) Outreach Program (Sohag course). 28-30 Dec 2017, Sohag, Egypt.
 Conference of Japanese Society of Inherited Metabolic Diseases (JSIMD 58). 27-29 Oct 2016, Tokyo, Japan.
 The 13th International Congress of Human Genetics (ICGH). 3-7 Apr 2016, Kyoto, Japan.
 The Egyptian Congress of Pediatric Pulmonology. 27-29 May 2015, Bibliotheca Alexandrina, Egypt.
 2nd Sohag Cardiology Conference (Common Neonatal Cardiac Problems). 25 Mar 2015, Sohag, Egypt.
 4th Sohag Neuropediatrics Conference. 4 Mar 2015, Sohag, Egypt.
 14th Annual Conference of the Egyptian Society of Pediatric Nephrology and Transplantation (ESPNT). 8-10 May 2014, Cairo, Egypt.
 9th Scientific Annual Conference of Sohag Faculty of Medicine (Applied scientific Researches; a fact or fiction?), 24-25 Apr 2014, Sohag, Egypt.
 1st Sohag Cardiology Conference (Updates in Childhood Cardiomyopathy). 27 Mar 2014, Sohag, Egypt.
 1st Assiut Neuropediatrics Conference. 27 Feb 2014, Assiut, Egypt.
 1st Sohag Haematology Conference. 23 Jan 2014, Sohag, Egypt.
 3rd Sohag Neuropediatrics Conference. 26 Dec 2013, Sohag, Egypt.
 The Egyptian Society of Nephrology and Transplantation (ESNT) Outreach Program. 5-6 Dec 2013, Sohag, Egypt.
Page 9 of 10
 1st Upper Egypt Neuroscience. 12-13 Sep 2012, Hurghada, Egypt.
 11th Assiut pediatrics conference (Pediatrics Guidelines). 29-31 Mar 2012, Hurghada, Egypt.
 4th Beni-Suef Pediatrics conference (Advances in pediatrics). 23-24 Feb 2012, Hurghada, Egypt.
 Pediatric postoperative cardiac intensive care. 18-19 Jan 2012, Cairo, Egypt.
 6th Upper Egypt Pediatric Congress. 8-10 Dec 2011, Hurghada, Egypt.
 3rd Beni-Suef Pediatrics conference (Pediatricians’ Concerns). 18-20 May 2011, Hurghada, Egypt.
 The Scientific Annual Meeting of Sohag Faculty of Medicine (Environmental pollution and Medical Problems in Upper Egypt). 5-6 Apr 2007, Sohag, Egypt.

WORKSHOPS

 ASU-MENA-FRI Academic leader Training (Manage the Change). 25 Jul 2018, Faculty of Medicine-Ain Shams University, Cairo, Egypt.
 10th National Workshop in Medical Education. 1 Jul 2018, Faculty of Medicine, Suez-Canal University, Ismailia, Egypt.
 1st workshop of Sohag University Hospital PICU. 11 Apr 2018, Department of Pediatrics, Sohag University, Sohag, Egypt.
 Scientific Supervision on dissertations. 18-20 Feb 2018, Medical Education Development Center, Sohag University, Sohag, Egypt.
 Training of Trainers. 17-27 Feb 2018, Faculty Leadership Development Center, Sohag University, Sohag, Egypt.
 Design Your Effective Training Course Step by Step. 27 Dec 2017, DAAD Kairo AKademie, Cairo, Egypt.
 Writing Scientific Papers. 24-25 Dec 2017, Medical Education Development Center, Sohag University, Sohag, Egypt.
 Thinking Skills. 23-25 Dec 2017, Faculty Leadership Development Center, Sohag University, Sohag, Egypt.
 Statistical Analysis in Scientific Research. 16-18 Dec 2017, Faculty Leadership Development Center, Sohag University, Sohag, Egypt.
 International Publishing of Research. 09-11 Dec 2017, Faculty Leadership Development Center, Sohag University, Sohag, Egypt.
 Basics of Neonatal Mechanical Ventilation. 19-21 Jul 2017, Department of Pediatrics, Sohag University, Sohag, Egypt.
 Proposal Writing & Research Writing (AuthorAID). 18 Apr-12 Jun 2017, AuthorAID&INSAP (Online course).
 Pediatric Emergencies II. 17-18 Jun 2015, Department of Pediatrics, Sohag University, Sohag, Egypt.
 Pediatric Emergencies I. 10-11 Jun 2015, Department of Pediatrics, Sohag University, Sohag, Egypt.
 Radiological procedures for pediatric pulmonary diseases. 27-29 May 2015, the Egyptian congress of pediatric pulmonology, Bibliotheca Alexandrina, Egypt.
 Neonatal Ventilation Course. 15-16 Apr 2015, the National Training Institute, Ministry of Health, Cairo, Egypt.
 Diagnosis, Prevention and Therapy of genetic disorders. 7-12 Feb 2015, Ain-Shams Faculty of medicine, Cairo, Egypt.
 Training Program for Maternal & Child Health and Nutritional care. 27-28 Feb 2014, MCHIP Egypt, Sohag, Egypt.
 41st workshop of Training of Academics.10-20 Feb 2014, Faculty of Education, Sohag University, Sohag, Egypt.
 Proposal writing GERLS. 26 Sep 2013, DAAD Kairo AKademie, Cairo, Egypt.
 NU 100; Entrepreneurship course. Summer 2013, Nile University, Egypt.
 Basic Principles & Clinical Applications of PCR. 16-18 Jun 2013, Central Research Laboratory, Sohag, Egypt.
 Diagnosis & Therapy of genetic disorders and congenital anomalies. 9-14 Feb 2013, Ain-Shams Faculty of medicine, Cairo, Egypt.
 Neonatal Resuscitation Training Provider Course (Standardized by the American Academy of Pediatrics). 17-18 Jan 2013 Future Pediatricians Society, Luxor, Egypt.
 Update of Pediatric Nutrition. 10 Jan 2013, Department of Pediatrics, Sohag University, Sohag, Egypt.
 Basic and Advanced Modes of Mechanical Ventilation in Infants and Children. 28-29 Nov 2012, Department of Pediatrics, Sohag University, Sohag, Egypt.
 Pediatric Fundamental Critical Care Support (PFCCS) Course. 30 Jun & 1 Jul 2012, Society of critical care medicine, Assiut University Children Hospital, Assiut, Egypt.
 Recent advances in management of critically ill patients in ICU. 30-31 Dec 2011, Department of Critical Care, Sohag University, Sohag, Egypt.
 Breast feeding promotion and support in a baby friendly hospital (UNICEF and WHO Course). 13-15 Sep 2011, Mother and Child Friendly Care Association (MCFC), Sohag, Egypt.
 Credit hours. 5-7 Jul 2011, Medical Education Development Center, Sohag University, Sohag, Egypt.