Background/Objectives: Acne vulgaris is a common inflammatory skin disease. Vitamin D deficiency plays a role in many inflammatory skin diseases. It may play a role in pathogenesis of acne vulgaris. This study aimed to assess serum levels of 25 hydroxy vitamin D in patients with acne vulgaris before and after treatment with isotretinoin and its relation with acne vulgaris severity. ... Read more

Leser-Trélat syndrome (LTS) is a rare cutaneous paraneoplastic syndrome that barely affects patients with head and neck cancer. Here we present a case of 58-years old male presented with skin manifestation consistent with a sign of Leser-Trélat. A close investigation of the patient revealed that he had a recurrent laryngeal squamous cell carcinoma. The described case is the fifth case ... Read more

Psoriasis is one of the most common chronic, inflammatory, T-cell-mediated autoimmune diseases. Narrow-band UVB (NB-UVB) therapy is widely used in the treatment of psoriasis; however, its mechanism of action is still not well understood. The objective of this study was to investigate the circulating T-lymphocyte subpopulations in psoriasis patients before and after NB-UVB, to get insights into the mechanism of ... Read more

Background: Skin diseases are a major health problem affecting a high proportion of the population and causing distress and disability. Disabled children may be particularly susceptible to skin disorders. Data regarding the dermatological problems encountered among physically and/or mentally challenged children are limited in Egypt. Objectives: The present study aimed to determine the pattern and the prevalence of skin diseases ... Read more

OBJECTIVES: The objective of this study was to assess the clinical presentations of perianal warts in boys and to evaluate the possible relationship between the presence of perianal warts and the sexual abuse as mode of transmission. MATERIALS AND METHODS: In a prospective clinical study, it conducted on 16 boys with clinically evident perianal warts at the Department of Dermatology, ... Read more

BACKGROUND: Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are characterized by widespread epidermal necrosis and mucosal involvement secondary to keratinocyte apoptosis induced mostly by drugs and associated with high mortality. OBJECTIVE: To examine the prevalence, etiology, clinical presentations, and outcome of SJS/TEN in patients admitted in the Department of Dermatology, Venereology, and Andrology, Faculty of Medicine, Sohag University, Sohag, ... Read more

BACKGROUND: Acne vulgaris is the most common dermatological condition encountered in adolescents. AIM: It was to determine the prevalence of acne vulgaris and its impact of the quality of life among adolescents attending secondary schools in Sohag Province, Upper Egypt. PATIENTS AND METHODS: This was a cross-sectional study conducted in randomly selected governmental and technical secondary schools in Sohag Province, ... Read more

SUMMARY: The aim of the study wasto compare the clinical efficacy and safety of the on-demand use of paroxetine, dapoxetine, sildenafil and combined dapoxetine with sildenafil in treatment of patients with premature ejaculation (PE).In a single-blind placebo-controlled clinical study, 150 PE patients without erectile dysfunction (ED) were included during the period of March 2015 to May 2016. Patients were randomly ... Read more

Premature Ejaculation (PE) is the most common male sexual dysfunction. This study was aiming to investigate the role of serum testosterone, gonadotropins and prolactin in patients with PE. In a prospective a case-controlled study, it was conducted on 90 male patients with PE and 90 male healthy participants as controls. Patients were evaluated by Premature Ejaculation Diagnostic Tool (PEDT) and ... Read more

Background: Chronic radio dermatitis is a frequent side effect of radiotherapy. It may be associated with decreased quality of life. Aims: The aim of this study was to evaluate the clinical efficacy and safety of intralesional injection of triamcinolone acetonide for the treatment of patients with chronic radio dermatitis. Methods: This study was a prospective clinical trial conducted on 30 ... Read more