Background Psoriasis is a common and complex multifactorial disease, in which both genetic and extrinsic factors contribute to activating an immunological reaction. Objectives This study aimed to evaluate the clinical, demographic, and laboratory characteristics of Egyptian psoriatic patients in Sohag, Upper Egypt. Patients and methods This study was a cross-sectional hospital-based study conducted on 200 Egyptian psoriatic patients. All the ... Read more

Different modalities are used for treatment of common warts, but none of them had been proved to be the best in achieving complete cure. We aim to compare the effect of cryotherapy, intralesional injection of tuberculin PPD and cryotherapy combined with intralesional injection of tuberculin PPD in the treatment of multiple common warts. This study is a randomized clinical trial ... Read more

Abstract Background:Psoriasis is a chronic inflammatory skin disease that not fully understood till now. Many treatment options has been implicated. Omentin 1 is anew marker implicated in many diseases. Objectives:To show association betweenserum level of Omentin-1 in psoriatic patients and its correlation with psoriasis area and severity index (PASI) score before and after treatment with narrow band ultraviolet B phototherapy ... Read more

Background: Acne is a multifactorial and inflammatory disease of pilosebaceous follicles, which affects most adoles-cents. Metabolic Syndrome (MetS) is a multiplex syndrome and has been reported to be associated with many dermatologic diseases, such as acne vulgaris. Aim of Study: Study the prevalence of MetS in post-adolescent male patients with AV (aged >!20 years), and assess the relation between MetS ... Read more

Alopecia areata is the most prevalent autoimmune disorder which causes non-scarring hair loss. It may increase the anxiety of patients and increase their chances of developing psychological and psychiatric disorders. There are two proposed theories for the pathogenesis of alopecia areata. The most evidence-based hypothesis is an autoimmune reaction caused by the collapse of hair follicle immune privilege, Immune privilege ... Read more

INTRODUCTION AND OBJECTIVE: 10 -20% of infertile men suffer from azoospermia of which up to 60% is presumed to have a non-obstructive (NOA) cause. Whilst there have been studies showing improved sperm retrieval rates (SSR) in men with NOA and low Testosterone by treatment with clomiphene, Human chorionic gonadotropin (hCG) and human menopausal gonadotropin (hMG), no treatment protocols have consistently ... Read more

Vitiligo is an acquired skin disorder that is characterized by a gradual loss of skin pigmentation when melanocytes, the skin's pigment-producing cellsis lost. Pathogenicmechanisms are not well understood. Genetic, abnormal biochemical pathways, autoimmune, melanocyte adhesion deficits and nervous system imbalances are among the pathogenic triggers. Vitiligo lesions have also been shown to have macrophage infiltration.Macrophagemigration inhibitory factor (MIF) is a ... Read more

To verify and compare the therapeutic efficacy and safety of superficial cryotherapy using dimethyl ether and propane (DMEP) mixture vs. microneedling in the treatment of mild scalp alopecia areata (AA). In a prospective randomized single-blinded clinical trial, 80 patients with clinically evident scalp mild AA were randomly assigned into two groups of 40 patients each. Group (1) was treated by ... Read more

Abstract: Alopecia areata is a common cause of nonscarring alopecia, with patchy, confluent, or diffuse patterns, involving mainly the scalp and other hairy areas of the body. It's considered a therapeutic challenge due to prognosis, unpredictable course, and variable efficacy of available therapies. Several studies have evaluated the efficacy of cryotherapy in the treatment of alopecia areata with varying success ... Read more

Purpose: Psoriasis vulgaris, one of the most prevalent chronic inflammatory skin diseases, is associated with metabolic syndrome (MetS). Autophagy, an intracellular degradation system is essential for cell survival and differentiation, and its dysfunction may contribute to metabolic diseases. A cross-sectional study was conducted on 38 psoriasis vulgaris patients and 16 healthy control subjects to 1) Assess immunohistochemical (IHC) expression of ... Read more