essameldin_nada

Essameldin Abdelaziz Mohamed Ahmed Nada

Professor - Prof. of Dermatology,Venereology and Andrology

Faculty of medicine

Address: 8 Abou Bakr ElSedik Dokki Giza

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Macrophage Migration Inhibitory Factor in Vitiligo: Pathogenesis and Potential Therapeutic Aspects.

2021 | Keywords Vitiligo pathogenesis macropha,
Macrophage Migration Inhibitory Factor in Vitiligo: Pathogenesis and Potential Therapeutic Aspects.
Vitiligo is an acquired skin disorder that is characterized by a gradual loss of skin pigmentation when melanocytes, the skin's pigment-producing cellsis lost. Pathogenicmechanisms are not well understood. Genetic, abnormal biochemical pathways, autoimmune, melanocyte adhesion deficits and nervous system imbalances are among the pathogenic triggers. Vitiligo lesions have also been shown to have macrophage infiltration.Macrophagemigration inhibitory factor (MIF) is a ... Read more

Superficial cryotherapy, does it work in alopecia areata?.

2021 | Keywords
Superficial cryotherapy, does it work in alopecia areata?.
Abstract: Alopecia areata is a common cause of nonscarring alopecia, with patchy, confluent, or diffuse patterns, involving mainly the scalp and other hairy areas of the body. It's considered a therapeutic challenge due to prognosis, unpredictable course, and variable efficacy of available therapies. Several studies have evaluated the efficacy of cryotherapy in the treatment of alopecia areata with varying success ... Read more

Superficial cryotherapy using dimethyl ether and propane mixture versus microneedling in the treatment of alopecia areata: A prospective single-blinded randomized clinical trial.

2021 | Keywords alopecia areata; microneedling,
Superficial cryotherapy using dimethyl ether and propane mixture versus microneedling in the treatment of alopecia areata: A prospective single-blinded randomized clinical trial.
To verify and compare the therapeutic efficacy and safety of superficial cryotherapy using dimethyl ether and propane (DMEP) mixture vs. microneedling in the treatment of mild scalp alopecia areata (AA). In a prospective randomized single-blinded clinical trial, 80 patients with clinically evident scalp mild AA were randomly assigned into two groups of 40 patients each. Group (1) was treated by ... Read more

Assessment of LC3 autophagy marker in psoriasis vulgaris patients with metabolic syndrome: a cross-sectional study

2021 | Keywords Psoriasis Vulgaris, Psoriasis,
Assessment of LC3 autophagy marker in psoriasis vulgaris patients with metabolic syndrome: a cross-sectional study
Purpose: Psoriasis vulgaris, one of the most prevalent chronic inflammatory skin diseases, is associated with metabolic syndrome (MetS). Autophagy, an intracellular degradation system is essential for cell survival and differentiation, and its dysfunction may contribute to metabolic diseases. A cross-sectional study was conducted on 38 psoriasis vulgaris patients and 16 healthy control subjects to 1) Assess immunohistochemical (IHC) expression of ... Read more

Assessment of the Effect of Metabolic Syndrome on the Autophagy Marker LC3 in Psoriasis Vulgaris Patients: A Cross-Sectional Study.

2020 | Keywords Psoriasis Vulgaris,
Assessment of the Effect of Metabolic Syndrome on the Autophagy Marker LC3 in Psoriasis Vulgaris Patients: A Cross-Sectional Study.
Purpose: Psoriasis vulgaris, one of the most prevalent chronic inflammatory skin diseases, is associated with metabolic syndrome (MetS). Autophagy, an intracellular degradation system is essential for cell survival and differentiation, and its dysfunction may contribute to metabolic diseases. A cross-sectional study was conducted on 38 psoriasis vulgaris patients and 16 healthy control subjects to 1) Assess immunohistochemical (IHC) expression of ... Read more

Role of Therapy Using Human Chorionic Gonadotropin and Anti-oxidants in Post Varicocelectomy Infertile Patients.(Randomized Clinical Trial)

2020 | Keywords Infertility, Varicocele, varic,
Role of Therapy Using Human Chorionic Gonadotropin and Anti-oxidants in Post Varicocelectomy Infertile Patients.(Randomized Clinical Trial)
AIM OF THE WORK: To evaluate the effect of human chorionic gonadotropin and antioxidants on semen parameters after varicocelectomy in infertile patients. PATIENTS AND METHODS: This is a randomized prospective clinical trial. This study included 60 varicocele infertile patient with oligoasthenoteratozoospermia (OAT) undergo varicocelectomy. Patients were randomly divided into four groups : Patients in group (A) were treated with HCG ... Read more

Erbium-yag laser alone versus erbium-yag laser with platelet rich plasma in treatment of atrophic acne scars .

2020 | Keywords Acne scars; Erbium-YAG laser;,
Erbium-yag laser alone versus erbium-yag laser with platelet rich plasma in treatment of atrophic acne scars .
AIM OF THE WORK : To evaluate the efficacy of Erbium-YAG laser alone and in combination of platelet-rich plasma (PRP) in atrophic post acne scars. PATIENTS AND METHODS: This study was a prospective non randomized clinical trial. 50 patients were included in this study, examined and divided into two groups. Group A included 25 patients were subjected to 6 Erbium-YAG ... Read more

Diagnosis of onychomycosis clinically by nail Dermoscopy versus microbiological diagnosis.

2020 | Keywords Fungal culture, KOH, Nail dermoscopy, Onychomycosis,
Diagnosis of onychomycosis clinically by nail Dermoscopy versus microbiological diagnosis.
Diagnosis of onychomycosis requires microbiological studies, which are time-consuming. Dermoscopy is non invasive, easy and coastless method. To evaluate the diagnostic role of dermoscopy in onychomycosis and comparing its findings with microbiological results. Eighty patients with onychomycosis and 40 controls were studied for nail dermoscopic finding, and microbiological examinations in the form of microscopic examination by 20% KOH, Sabouraud dextrose ... Read more

Lesional and circulating levels of interleukin‐17 and 25‐ hydroxycholecalciferol in active acne vulgaris: Correlation to disease severity

2019 | Keywords Western blot, IL‐17, Immunohistochemistry, ELISA, acne, 25(OH)D3,
Lesional and circulating levels of interleukin‐17 and 25‐ hydroxycholecalciferol in active acne vulgaris: Correlation to disease severity
OBJECTIVES: The immunological aspects of inflammatory acne are still incompletely understood, so this study aimed to investigate the possible role of IL‐17 and 25 hydroxycholecalciferol (25(OH)D3) in the disease pathogenesis and progression. MATERIALS AND METHODS: Across‐sectional study has been conducted on 135 patients with active acne vulgaris of various severities and 150 matched controls. ELISA assays of serum and tissue ... Read more

Efficacy of microneedling with topical vitamin C in the treatment of melasma.

2019 | Keywords microneedling, melasmsa, micronee, melasma, dermaroller,
Efficacy of microneedling with topical vitamin C in the treatment of melasma.
Summary Background: Despite the wide therapeutic options available for the treatment of me‐ lasma, including many active topical medications, technologies with lights and peel‐ ings, clinical control of this disorder is extremely challenging. Objectives: To evaluate the effect of microneedling with topical vitamin C in the treatment of melasma. Methods: Thirty female patients with melasma received six sessions of micronee‐ ... Read more