INTRODUCTION Aging represents a major risk for vascular diseases. Diseases of the aorta exert serious effects on the heart. AIM This study aimed to detect the histological changes of the aged aorta, understand their underlying mechanisms, and help in the development of prophylactic and treatment measures. MATERIALS AND METHODS Ten adult and 10 aged male albino rats were used. Specimens ... Read more

Abstract: Background: Saliva composition shows hormone related changes suggesting that hormones may have a role in the control of salivary gland functions. Aim of the work: The aim of this work is to throw light on the effect of female sex hormones on the submandibular salivary gland. Material and methods: A total number of 50 adult female Albino rats were ... Read more

OBJECTIVE: To compare the gross and microscopic appearance of antrochoanal polyps associated with recurrent epistaxis, with those with a more typical presentation. DESIGN: Prospective, controlled study. METHODS: All patients underwent clinical and endoscopic examination, computed tomography scanning, and examination under anaesthesia, in order to detect the gross diagnostic criteria for antrochoanal polyp. Histological findings on light microscopy were compared for ... Read more

Objectives: We compared histologic findings on light microscopy of viscid secretions found in association with nasal polyps with those found in patients with chronic sinusitis without polyposis (CSWP). The differences might further understanding of nasal polyp pathogenesis. Methods: In a prospective controlled study, viscid secretions found in association with nasal polyps were collected at endoscopic sinus surgery. Retained secretions in ... Read more

BACKGROUND Cholesteatoma consists of keratinizing squamous epithelium, granulation tissue and keratin plugs. The pathogenesis of cholesteatoma may be related to alterations in the stromal immune cell infiltrate. OBJECTIVE To examine the immunophenotypic characteristics of the immune cell infiltrate in invasive cholesteatomas MATERIALS AND METHODS This study included 12 patients with invasive cholesteatomas causing wide bone erosion of the mastoid, middle ... Read more

Various clinical trials have documented the therapeutic benefit of glucocorticoids (GCs) in enhancing muscle strength and slowing disease progression of Duchenne and Becker muscular dystrophies (DMD/BMD). We hypothesized that GCs may have relevance to the differential anti-inflammatory effect on mononuclear inflammatory cells (MICs) and Dendritic cells (DCs) infiltrating the dystrophic muscles. In this prospective study, two muscle biopsies were obtained ... Read more

BACKGROUND: Hydatidiform mole is a gestational trophoblastic disease characterized by pro­liferation of the pregnancy-associated trophoblastic tissue. Complete hydatidiform mole is an entirely paternally derived lesion, and therefore, represents complete intrauterine allograft that can induce an altered maternal immune response Hypothesis: Here, we hypothesize that "the development of hydatidiform moles is associated with numeric alterations of the decid­ual immune cell infiltrate. ... Read more

This study examines the postoperative histologic changes in the nasal mucosa following treatment with amoxycilline or rifampicin. Three groups of nasal mucosal biopsies were obtained from 20 patients having undergone nasal surgery (partial middle turbinectomy). The first group was obtained immediately before surgery (control group). The second and third groups were taken postoperatively (after the first and 6 weeks of ... Read more

Comparative immunohistological and ultrastructural studies were performed on specimens taken before and after the application of chemical peels (Jessner’s solution and glycolic acid) and microdermabrasion to the clinically normal facial skin of the post-auricular region. Skin treated with chemical peels showed the immunohistological features of wound healing. Beside these, ultrastructural changes of cell injury were observed. These morphological changes were ... Read more

_Background_: Roentgen irradiation can affect normal cells, especially the rapidly growing ones such as the mucosal epithelial cells of the small intestine. The small intestine is the most radiosensitive gastrointestinal organ and patients receiving radiotherapy directed to the abdomen or pelvis may develop radiation enteritis. Although roentgen rays are widely used for both imaging and therapeutic purposes, our knowledge about ... Read more