Eman E Abu-Dief

Professor - professor of Histology,Faculty of Medicine,Sohag University

Faculty of medicine

Address: Histology Department- Faculty of medicine- Sohag University


2018 | Keywords liver, milk thistle, ultrastructure,
Ultrastructural, Histochemical and Biochemical effects of Titanium dioxide nanoparticles in Adult male albino rat liver and possible prophylactic effects of Milk thistle seeds.
Bachground: Lead is considered an important cause of the infertility among occupational workers .The present work was done to study the histological changes in the testicles of adult albino rats after lead treatment for different periods, and the role of vitamin E in minimizing these changes. Material and Methods: Forty five adult rats were used in this study. They divided ... Read more

Impact of omega-3 fatty acids on evolution of carbon tetrachloride- (CCl4) induced liver cirrhosis in mice : A histological and immunohistochemical study.
Introduction: Cirrhosis is the end stage of any chronic liver disease. It is characterized by diffuse fibrosis with disturbed hepatic architecture. Omega-3 polyunsaturated fatty acids are common antioxidant, anti-inflammatory and anti-fibrotic agents Aim: This study was conducted to investigate the potential effects of omega-3 fatty acids on experimentally induced cirrhosis. Materials and Methods: 60 animals were divided into three groups: ... Read more

Animal Models for Hepatic Fibrosis and Cirrhosis
Liver cirrhosis represents a major health problem. No effective anti-fibrotic therapy is available up till now. Understanding the pathogenesis of liver fibrosis is essential for developing new strategies for anti- fibrotic therapies. Animal models may be used for this purpose [1,2]. Animal models have several advantages compared to clinical studies including; the possibility of taking samples at different time-points, the ... Read more

2017 | Keywords hepatoblastoma, P53, EGF,
Expression of C-KIT Tyrosine Kinase Receptor, Epidermal Growth Factor, and p53 Proteins in the epithelial and mesenchymal cells of Hepatoblastoma: Preli.minary Findings
Background: Overexpression of receptor-type protein tyrosine kinases (PTKs) and alterations of p53 are well known events in neoplastic cells and are associated with an aggressive tumor phenotype. To date, our knowledge about PTKs and p53 expression in the neoplastic cells (epithelial and mesenchymal cells) of hepatoblastoma is incomplete. Objectives: This study tries to address this issue and test the hypothesis ... Read more

2017 | Keywords morphological changes, skin, pee,
Morphological changes of the skin following microdermabrasion and chemical peeling. .
Dermatologists and plastic surgeons use a variety of skin resurfacing and rejuvenating procedures to improve the skin appearance. Of these, chemical peels and microdermabrasion are simple and non-invasive procedures commonly used to alleviate some disorders such as acne, spots, scars, wrinkles, photo aging, stretch marks and to restore more youthful skin appearance [1,2]. These techniques cause skin injury either mechanically ... Read more

2017 | Keywords prostate, infarcts,
Prostatic infarct: A case report and review of literature
This study reports a 56 years old male patient with a history of sudden urinary retention and high level of prostatic specific antigen. Suprapubic transvesical prostatectomy was done and revealed enlarged prostate with a large, circumscribed area of infarction. On histology, a well-circumscribed zone of coagulative necrosis, haemorrhage, surrounding reactive squamous nests with reactive atypia (prominent nucleoli, and frequent mitoses) ... Read more

2017 | Keywords chemical peeling, collagen fib,
Dermal morphological changes following salicylic acid peeling and microdermabrasion.
Background: Microdermabrasion and chemical peeling are popular, inexpensive, and safe methods for treatment of some skin disorders and to rejuvenate skin. Objectives: To study the alterations of the dermal connective tissue following salicylic acid peeling and microdermabrasion. Methods: Twenty patients were participated in our study. All participants underwent facial salicylic acid 30% peel or microdermabrasion (10 cases in each group) ... Read more

2016 | Keywords
Expression of CD30, CD57 and CD99 Leukocyte  Antigens in Eczematous Dermatitis
ABSTRACT BACKGROUND: CD30 is a protein that belongs to the tumor necrosis factor receptor superfamily. Its expression was observed in increasing numbers of cutaneous inflammatory conditions. Natural killer cells (CD57 positive cells) have an important role in several inflammatory conditions of the skin. CD99 is a long-known leukocyte antigen expressed at the endothelial cell contacts. It participates in the transendothelial ... Read more

2016 | Keywords leptin, puberty, femal rats,
The effect of Leptin on the Onset of Puberty in Normal Prepubertal Female Albino Rats .
Background: Many studies have focused on leptin, the product of the LEP (ob) gene, searching for a possible link between energy balance and reproduction. Objective: Investigating the effect of daily leptin injection on prepubertal female rats and the possible mechanisms by which leptin can affect reproductive axis. Materials and method: This study was applied on eighty female albino rats weaned ... Read more

2015 | Keywords live, rats, TiO2 nanoparticles,
Histological Effects of Titanium Dioxide Nanoparticles in Adult Male Albino Rat Liver and Possible Prophylactic Effects of Milk Thistle Seeds. .
Abstract: Titanium dioxide nanoparticles (TiO2 NPs) are manufactured worldwide in large quantities for use in a wide range of applications including pigment, plastics, papers, inks, food colorants, toothpastes and cosmetic manufacturing. Milk thistle is a herbal supplement used to treat liver and biliary disorders. Silymarin, an active ingredient of Milk thistle, is a strong antioxidant that promotes liver cell regeneration ... Read more