hala_madkoor

Hala Ibraheem Madkour

استاذ مساعد - المرشد الاكاديمي للدكتوراه

كلية الطب

العنوان: كلية الطب

5

إعجاب
8 2 2 11 3 2 227 183
93

أضيف حديثا
  • المقررات الدراسية 8
  • ملحقات المقررات الدراسية 2
  • واجبات المقررات الدراسية 2
  • المنشورات و المؤلفات 11
  • ساعات مكتبية 3
  • الاعلانات 2
  • عدد الملفات المرفوعه 8
  • كل التنزيلات 6

METFORMIN ATTENUATES FREUND’S ADJUVANT INDUCED ARTHRITIS IN MALE RATS

2017 | الكلمات المفتاحية arthritis, Metformin,
METFORMIN ATTENUATES FREUND’S ADJUVANT INDUCED ARTHRITIS IN MALE RATS
ABSTRACT OBJECTIVE: Metformin is well known anti-diabetic agent. Recently many reports have described the anti-inflammatory effects of metformin on various cell types including human vascular smooth muscle cells and endothelial cells. This study was designed to investigate the anti-arthritic effects of metformin on Freund’s complete adjuvant (FCA)-induced arthritis in rats. METHODS: rats were randomly divided into 4 groups as follows: ... إقراء المزيد

Evaluation of the potential role of eugenol in induced arthritis and diabetes mellitus in rats

2017 | الكلمات المفتاحية eugenol, diabetes mellitus, Rheumatoid Arthritis,
Evaluation of the potential role of eugenol in induced arthritis and diabetes mellitus in rats
ABSTRACT BACKGROUND: Systemic inflammatory burden in rheumatoid arthritis (RA) has been shown to predispose to developing both insulin resistance and type 2 diabetes mellitus (DM). Polypharmacy with cumulative side effects are common problems met with in these medical situations of combined diseases. AIM OF THE WORK: the present study evaluates the potential role of eugenol as a natural product with ... إقراء المزيد

Eugenol ameliorates letrozole induced polycystic ovary syndrome in rats

2016 | الكلمات المفتاحية letrozole, polycystic ovary, eugenol,
Eugenol ameliorates letrozole induced polycystic ovary syndrome in rats
ABSTRACT BACKGROUND: It is now evident that there is a strong association between oxidative stress and chronic low grade inflammation in polycystic ovary syndrome (PCOS) pathogenesis. Therefore, simultaneous targeting of these pathways by eugenol which has dual anti-inflammatory and anti-oxidant potential might be a therapeutic alternative approach to the current treatment. This study was designed to evaluate the dual targeting ... إقراء المزيد

Protective Effect of Lycium Barbarum Extract as Antioxidant Agent on Roridin A: Induced Hepatotoxicity in Male Rat

2015 | الكلمات المفتاحية ANTIOXIDANT,
Protective Effect of Lycium Barbarum Extract as Antioxidant Agent on Roridin A: Induced Hepatotoxicity in Male Rat
Abstract The fruit goji berry of Lyciumbarbarym, a traditional Chinese herbal medicine, has been widely used in healthy diets due to its potential role in the prevention of chronic diseases. We studied the effects ofroridin A toxin in male rat liver and their amelioration by goji extract. Thirtymale adult albino rats were divided into three groups (10 rats each). Group ... إقراء المزيد

Diallyl disulfide, from garlic oil, synthesizes human colonic adenocarcinoma cell line (Caco-2) to TNF-alpha mediated apoptosis through up-regulation of membrane FAS levels

2013 | الكلمات المفتاحية Diallyl disulfide, garlic oil, TNF alpha, FAS,
Diallyl disulfide, from garlic oil, synthesizes human colonic adenocarcinoma cell line (Caco-2) to TNF-alpha mediated apoptosis through up-regulation of membrane FAS levels
Abstract: Colon cancer cells resistance to apoptosis inducing factors, particularly those working through the extrinsic apoptotic rout, such as Tumour necrosis factor alpha (TNF-α), may due to that these cells lack of the presence of FAS receptor on their membrane, to which TNF-α binds and causes the recruitment of caspase-8 and other caspases cascade required in apoptotic cell death. In ... إقراء المزيد

ANTIBIOTIC RESISTANCE PATTERN OF BACTERIAL PATHOGENS IN THE NEONATAL INTENSIVE CARE UNIT OF SOHAG UNIVERSITY HOSPITAL

2012 | الكلمات المفتاحية
ANTIBIOTIC RESISTANCE PATTERN OF BACTERIAL PATHOGENS IN THE NEONATAL INTENSIVE CARE UNIT OF SOHAG UNIVERSITY HOSPITAL
Background: Antimicrobial-resistant pathogens are of increasing concern in the neonatal intensive care unit population. A myriad of resistance mechanisms exist in microorganisms and management can be complex because broad-spectrum antibiotics are increasingly needed. Objective: To study the bacterial pathogens causing neonatal sepsis and their sensitivity pattern so that guidelines can be prepared for empirical antibiotic therapy. Setting: The study was ... إقراء المزيد

Hypoglycemic Effect of Eugenol vs Glibenclamide in Alloxan Induced Diabetic Rats

2011 | الكلمات المفتاحية , diabetes mellitus, alloxan, clove oil, eugenol,
Hypoglycemic Effect of Eugenol vs Glibenclamide in Alloxan Induced Diabetic Rats
Background: Diabetes mellitus is associated with deterioration of glycemic control and progressive metabolic derangements. Despite of introducing various hypoglycemic agents, diabetes and its complications continue to be major problem. Thus searching for a new class of compounds is essential to overcome diabetic problems and side effects of its treatment. Aim of the Work: This study investigated the effect of eugenol ... إقراء المزيد

Modification of antiinflammatory, antipyretic and analgesic effects of celecoxib with some antiulcer drugs in experimental animals

2008 | الكلمات المفتاحية COX2, Peptic ulcer, celecoxib,
Modification of antiinflammatory, antipyretic and analgesic effects of celecoxib with some antiulcer drugs in experimental animals
Patients under antiulcer therapy may suffer from a concurrent disease which requires the use of one of NSAIDs, In such cases, these patients are likely to receive a combination of one of the antiulcer drugs plus the NSAIDs. Accordingly, the simultaneous use of one of the NSAIDs with one of the antiulcer drugs may lead to drug-drug interaction. The present ... إقراء المزيد

Evaluation of the Possible Role of Cyclooxygenase-2 in Endometriosis

| الكلمات المفتاحية cytokines, Endometriosis, cyclooxygenase-2,
Evaluation of the Possible Role of Cyclooxygenase-2 in Endometriosis
Abstract: Endometriosis is a common, complex and chronic disease related to ectopic implantation and growth of endometrial tissue. Endometriosis is characterized by the presence and/or the growth of endometrial tissue (both glands and stroma) outside the uterine cavity that causes inflammation inside or outside the pelvis. This study aimed to investigate the possible role of COX-2 in endometriosis and its ... إقراء المزيد

Eugenol Ameliorates Freund’s Adjuvant Induced Arthritis in Male Rats

| الكلمات المفتاحية Rheumatoid Arthritis, adjuvant arthritis, eugenol,
Eugenol Ameliorates Freund’s Adjuvant Induced Arthritis in Male Rats
ABSTRACT BACKGROUND: Rheumatoid arthritis (RA) is a chronic relapsing autoimmune disorder. Eugenol, a main component of clove oil, possesses potent anti-inflammatory and antioxidant activity. Present investigation was designed to evaluate anti-arthritic potential of eugenol in Freund’s Complete Adjuvant (FCA) induced arthritis in male albino rats. MATERIALS AND METHODS: Thirty two male albino rats were used. Eight male rats were used ... إقراء المزيد