mamdouh.fawzi

Mamdouh Fawzy Ahmed Mohamed

Lecturer - Lecturer of Pharmaceutical Chemistry, Head of Pharmaceutical Chemistry Department Lab and Co-ordinate of Clinical Pharmacy Program

Faculty of Pharmacy

Address: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt

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Publications Which contain the keyword: ApopTag

Immunohistochemical Study, In Situ Hybridization and Computerized Image Analysis of Colorectal Epithelial Progression from Adenoma to Carcinoma

2018-10-22 21:36:49 Keywords Carcinoma, adenoma, Colorectal, ApopTag, Ki-67., P53, Bax, Bcl-2,
Immunohistochemical Study, In Situ Hybridization and Computerized Image Analysis of Colorectal Epithelial Progression from Adenoma to Carcinoma
SUMMARY: Adenoma-carcinoma sequence was postulated for most colorectal carcinomas. Deregulation of apoptosis and cellular proliferation is involved in the pathogenesis of neoplasia. The apoptotic genes that have been characterized in colon cancer are bcl-2, bax, and p53. Studying the expression of these genes and of the proliferating cell marker (Ki-67) in adenoma carcinoma sequence well be of great value in ... Read more

Apoptosis and Colorectal Carcinoma; a Multiparameter Immunohistochemical, and Computerized Image Analysis Study

2018-10-22 22:17:49 Keywords Carcinoma, Colorectal, ApopTag, Ki-67, P53, Bax, Bcl-2,
Apoptosis and Colorectal Carcinoma; a Multiparameter Immunohistochemical, and Computerized Image Analysis Study
ABSTRACT: The last few years showed an increase in the incidence of the colorectal cancer in Egypt. Between 20% and 50% of patients with this cancer are susceptible to death within five years of diagnosis. Tumor growth results from a disturbance in the balance between the rates of cell proliferation and cell death (apoptosis). We studied the expressions of proteins ... Read more

Markers defining colorectal adenoma-carcinoma progression: a computerized image analysis protocol

2018-10-23 20:22:05 Keywords Colorectal cancer, adenoma, Carcinoma, , Bcl-2, Bax , P53, Ki-67, , ApopTag, , β-Catenin,
Markers defining colorectal adenoma-carcinoma progression: a computerized image analysis protocol
ABSTRACT: The vast majority of colorectal carcinoma are widely believed to arise from polypoid adenomas. The apoptotic related genes that have been most consistently characterized in colonic cancer are bcl-2, bax, and p53. Studying the expression of these genes in adenoma carcinoma sequence will be of great value in producing the clinical behavior of benign tumors. Loss of contact inhibition ... Read more

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