ABSTRACT Organophosphorus insecticides (OPs) exert their toxic effect through inhibition of acetylcholinesterase (AchE). In addition, accumulated evidences indicated that oxidative stress involved in OPs neurotoxicity and cytotoxicity. However, the mechanism underlay OPs induces oxidative stress still so far unclear. Recent reports were focused on the role of paraoxonase (PON), the HDL-associated A-esterase, in the degradation of the oxon form of ... إقراء المزيد