Purpose of ReviewMarek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes various clinical symptomsincluding fatal lymphomas in chickens. The virus encodes several MDV-specific genes that play a major role in viral pathogen-esis. This review will focus on the recent advances in our understanding of how these viral factors contribute to pathogenesis andtumor formation.Recent FindingsSeveral viral factors involved in ... Read more

Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs. Despite many years of research, the viral transcriptome in primary target cells of MDV remained unknown. In this study, we uncovered the transcriptional landscape of the very virulent ... Read more