The differential diagnosis of tuberculous and malignant pleural effusion (PE) is extremely difficult and continues to pose clinical challenges. Aim of the study: To evaluate the utility of pleural fluid interferon gamma (IFN-c), tumor necrosis factor-alpha (TNF-a), adenosine deaminase (ADA) levels with T cells subsets in differential diagnosis of malignant (MPE) and tuberculous pleural effusions (TPE). Methods: Forty patients with ... إقراء المزيد

There is no gold standard method for detecting latent tuberculosis infection (LTBI) in end stage renal disease (ESRD), the use of tuberculin skin test(TST) remains controversial due to its high rate of false results, new interferon gamma release assays have been developed for diagnosing LTBI as the QuantiFERON-TB Gold test(QFT-G). The aim of this work was to evaluate the value ... إقراء المزيد

Autoimmune endocrine disorders are considered one of the extrahepatic manifestations of Hepatitis C virus (HCV) infection. HCV could trigger cytokines release due to local inflammation. Interleukin 17 a (IL17a) and Interferon gamma (IFNγ) play an important role in pathogenesis of autoimmune disease. Herein, we tried to assess the serum levels of IL17a and IFN-gamma in cirrhotic HCV infected patients with ... إقراء المزيد