_Apelin, an endogenous peptide exerts its actions through binding to its receptors (APJ receptors) and has been demonstrated in both animal and human studies to have inotropic, diuretic (nitric oxide-dependent), and vasodilator effects, in addition to antagonistic effects on angiotensin II. In this investigation, serum apelin, nitric oxide (NOx), sodium (Na) and potassium (K) were evaluated in patients with essential ... Read more

ABSTRACT OVER THE PAST DECADE, MUCH HAS CHANGED ON THE LANDSCAPE OF MENINGITIS. THE PURPOSE OF THIS STUDY WAS TO INVESTIGATE THE INVOLVEMENT OF NITRIC OXIDE (NO) AND TUMOR NECROSIS FACTOR ALPHA (TNF-A) IN THE PATHOGENESIS OF CHILDHOOD MENINGITIS. WE MEASURED THE CONCENTRATION OF NO-2 (A STABLE METABOLITE OF NO) AND TNF- A IN SERIAL SAMPLES OF CEREBROSPINAL FLUID (CSF) ... Read more

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