mamdouh.fawzi

Mamdouh Fawzy Ahmed Mohamed

Lecturer - Lecturer of Pharmaceutical Chemistry, Head of Pharmaceutical Chemistry Department Lab and Co-ordinate of Clinical Pharmacy Program

Faculty of Pharmacy

Address: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt

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Publications Which contain the keyword: superoxide dismutase

Differential tolerance to high salt with regard to cell growth and superoxide dismutase (SOD) activity in calluses of the halophyte Suaeda maritima from Japan and Egypt

2018-11-25 00:12:16 Keywords suaeda maritima, callus, salt tolerance, superoxide dismutase, 2, 4-D_2.4-dichlorophenoxyaceti,
Differential tolerance to high salt with regard to cell growth and superoxide dismutase (SOD) activity in calluses of the halophyte Suaeda maritima from Japan and Egypt
To determine the mechanism of regulation of superoxide dismutase (SOD; EC 1.15.1.1) isozymes in halophytes at the cellular level,we isolated calluses from Suaeda maritima plants native to Japan and Egypt. Calluses from Egyptian S. maritima could grow in a high salt medium (~400 mM NaCl), whereas Japanese S. maritima calluses could not. The expression characteristics of SOD isozyme genes encoding ... Read more

Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction

2018-09-08 12:56:27 Keywords superoxide-nitric oxide, superoxide dismutase, db/db mice, Renal injury,
Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction
ABSTRACT: The effects of overexpression of Cu(2+)/Zn(2+) superoxide dismutase-1 (SOD-1) on indexes of renal injury were compared in 5-month-old nontransgenic (NTg) db/db mice and db/db mice hemizygous for the human SOD-1 transgene (SOD-Tg). Both diabetic groups exhibited similar hyperglycemia and weight gain. However, in NTg-db/db mice, albuminuria, glomerular accumulation of immunoreactive transforming growth factor-beta, collagen alpha1 (IV), nitrotyrosine, and mesangial ... Read more

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