On the basis of _N_-(pyrimidin-2-yl)cyanamides, a series of heterocyclic compounds of 2-aminopyrimidine derivatives: 2-(pyrimidin-2-ylamino)-4_H_-benzo[e][1,3]thiazin-4-ones, 2-(pyrimidin-2-ylamino)quinazolin-4(3_H_)-ones, _N_-(4-phenylpyrimidin-2-yl)quinazolin-2-amines, _N_-(5-aryl-1_H_-1,2,4-triazol-3-yl)pyrimidin-2-amines and _N_-(4-phenylpyrimidin-2-yl)-1_H_-benzo[d]imidazol-2-amine were produced. Read more

The method of synthesis of _N_-(pyrimidin-2-yl)cyanamides (_N_-(4-R-pyrimidin-2-yl), _N_-(5,6,7,8-tetrahydroquinazolin-2-yl)-, _N_-(5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-, _N_-(6,7-dihydro-5_H_-cyclopenta[d]pyrimidin-2-yl)-, _N_-(5-acetyl-4-methylpyrimidin-2-yl)-, _N_-(5-R’-6-oxo-1,6-dihydropyrimidin-2-yl)- and _N_-(5-methoxycarbonyl-4-methylpyrimidin-2-yl)cyanamides) based on interaction of 1-R-(3-dimethylamino)propenones, 2-ethoxymethylene or 2-dimethylaminomethylene derivatives of 1,3-dicarbonyl compounds with inexpensive commercially available cyanoguanidine has been designed. Read more