Design, Synthesis and Antibacterial Evaluation of some new 3,5-Diphenylcyclohex-2-en-1-one Derivatives
The moiety of cyclohexene has been showed highly antibacterial activity. New compounds were synthesized from diphenylcyclohexenone via reaction with a variety of reagents to afford branched chain of 1,3-diphenylcyclohexene or fused heterocyclic systems including pyrazole, chromen and pyrrole derivatives. Cyclic ketoketene _s,s_-acetal can be prepared by reaction with CS2/MeI under PTC conditions which in turn used as starting material for ... Read more