Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط



Publications Which contain the keyword: Steatosis

2018-10-21 04:40:40 Keywords liver, Steatosis, fatty acids,
Assessment of Hepatic Steatosis by Expert Pathologists The End of a Gold Standard
Background: The presence of fat in the liver is considered a major risk for postoperative complication after liver surgery and transplantation. The cur- rent standard of quantification of hepatic steatosis is microscopic evaluation by pathologists, although consistency in such assessment remains unclear. Computerized image analysis is an alternative method for objective assess- ment of the degree of hepatic steatosis. Methods: ... Read more

2018-10-21 04:44:13 Keywords liver, Steatosis, Fatty Acidso,
Prevention of Reperfusion Injury and Microcirculatory Failure in Macrosteatotic Mouse Liver by Omega-3 Fatty Acids
Macrovesicular hepatic steatosis has a lower tolerance to reperfusion injury than microvesicular steatosis with an abnormally high ratio of omega-6 (n-6): omega-3 (n-3) polyunsaturated fatty acids (PUFAs). We investigated the influence of PUFAs on microcirculation in steatotic livers and the potential to minimize reperfusion injury in the macrosteatotic liver by normalization of PUFAs. Ob/ob mice were used as a model ... Read more

2018-10-21 04:53:03 Keywords liver, Steatosis, Omega, Throm,
Chemical composition of hepatic lipids mediates reperfusion injury of the macrosteatotic mouse liver through thromboxane A2
Background & Aims: Chemical composition of hepatic lipids is an evolving player in steatotic liver ischemia/reperfusion (I/R) injury. Thromboxane A2 (TXA2) is a vasoactive pro-inflammatory lipid mediator derived from arachidonic acid (AA), an omega-6 fatty acid (X-6 FA). Reduced tolerance of the macrosteatotic liver to I/R may be related to increased TXA2 synthesis due to the pre- dominance of X-6 ... Read more

2018-10-21 04:58:56 Keywords liver, Steatosis, Transplantat,
When is steatosis too much for transplantation?
Steatosis is assessed according to the pattern and the amount of fatty infiltration in hepatic tissue sections. Traditionally, fatty accumulation has been classified morphologically as macrovesicular or microvesicular. Macrovesicular steatosis is characterised by a single, bulky fat vacuole in the hepatocyte that displaces the nucleus to the edge of the cell. Among a variety of dis- orders alcohol abuse, obesity, ... Read more

2018-10-02 13:30:04 Keywords HCV, IR, TyG, VAI, Steatosis, ,
Insulin Resistance, Visceral Adiposity Index and TyG Index in Genotype-4 Chronic HCV Patients and Their Relation to Hepatic Histopathology
Introduction: Hepatitis C virus (HCV) genotype 4 is the most prevalent in Egypt. Visceral adiposity index (VAI) and (TyG) index are newly developed indices for assessment of metabolic syndrome (MS) and insulin resistance (IR). We aimed at comparing their levels in HCV-patients with healthy controls and validate their use for prediction of hepatic histopathological changes. Patient and Methods: 78 chronic ... Read more

  • «
  • 1
  • »