This study reports a 56 years old male patient with a history of sudden urinary retention and high level of prostatic specific antigen. Suprapubic transvesical prostatectomy was done and revealed enlarged prostate with a large, circumscribed area of infarction. On histology, a well-circumscribed zone of coagulative necrosis, haemorrhage, surrounding reactive squamous nests with reactive atypia (prominent nucleoli, and frequent mitoses) and foci of squamous metaplasia) was identified. The diagnosis of prostatic infarct was established. A review of literature was presented.