This study was carried out to assess the influence of date palm pollen supplement on the productive performance, digestibility, immune response, and some morphological parameters of Fayoumi laying hens. One-hundred and fifty hens of 30-weeks of age were included in the study. The treated group was supplemented with 0.5% date palm pollen. The experiment was divided into three periods; each of them was 4 weeks. The obtained results showed a significant improvement in the cumulative egg production of the treated group. Eggs weight, mass and feed conversion revealed significant differences with date palm pollen supplementation. The digestibility of nutrients was increased through the experimental period, accompanied by positive morphological changes in the intestinal lumen, villi length, and crypt depth. Moreover, the immune response was significantly improved in the treated group. Finally we could recommend the supplementation of date palm pollen for laying hens through the production period and during stress