El-Sawi, N.M. and Al-Seeni, M.N. 2009. Assessment of flavonoids as rutin for detoxification of T-2 toxin.
J. Appl. Anim. Res., 35: 57-60.
To assess the efficacy of rutin, a flavonoid, for detoxifying T-2 toxin, 30 male albino rats were divided in
3 equal groups. Group 1 served as control. Rats in groups 2 and 3 were given 0.1 mg/kg bw T-2 toxin and
those of group 3 were given 50 mg/kg rutin additionally. Toxin in liver tissue increased TBARs, SOD,
GST, total lipids and decreased total thiol and catalase. Similarly there was increased lipid peroxide and
decrease in total thiol, GST, hemoglobin and hematocrit value. All these were improved in group 3. The
result suggest that rutin may be used as anti oxidant for T-2 toxin in liver of rat.
Key words: Mycotoxin T-2 toxin, trichothecene, rutin, antioxidants, serum, liver, hemoglobin.