CELL RESPONSE TO INJURY
Causes of Cell Injury
Mechanisms of Cell Injury
Effects of Cell Injury
Reversible cell injury (degeneration): include
Acute cellular swelling (cloudy swelling and hydropic swelling)
Fatty change
Irreversible cell injury: include
Necrosis
Apoptosis
CLOUDY SWELLING
Definition and pathogenesis
Features; organs affected and microscopic picture
Clinically picture and fate
HYDROPIC SWELLING
Definition, causes and pathogenesis
Microscopic picture
FATTY Change
Definition, etiology and pathogenesis
Gross and microscopic pictures and organs affected
NECROSIS
Definition, causes and pathogenesis
Macroscopic picture
Microscopic picture
Nuclear and cytoplasmic changes
Types of necrosis
Coagulative Necrosis
Liquefactive necrosis
Caseation necrosis
Fat necrosis
Fibrinoid necrosis
Fate of necrotic tissue
APOPTOSIS
Definition
Morphological changes
Occurrence
Differences between necrosis and apoptosis
GANGRENE
Definition and causes
Necrosis and putrefaction
Types
DRY GANGRENE
Senile Gangrene
Pathological features
MOIST GANGRENE
Moist gangrene of the intestine
Moist gangrene of the limb
Diabetic gangrene; causes and pathology
Differences between dry and moist gangrene
INFECTIVE GANGRENE
Types; lung gangrene, cancrum oris, noma pudenda, phagedena, synergistic gangrene and bed sores
GAS GANGRENE
