Introduction
  • Overview
    • pediatric femoral shaft fractures are one of the most common pediatric orthopedic fractures and are the most common reason for pediatric hospitalization due to orthopedic injury
      • treatment may be casting or operative depending on the fracture pattern and age of patient.
      • any femur fracture in a child not yet walking should raise concern for non-accidental trauma
  • Epidemiology
    • incidence
      • 1.6-2% of all pediatric fractures
        • bimodal distribution
          • increased rate in toddlers age 2-4 years and adolescents
      • most common reason for pediatric hospitalization due to orthopaedic injury
    • demographics
      • males more commonly affected 2.6:1
  • Pathophysiology
    • mechanism of injury
      • fall is the most common cause under 10 years
      • a motor vehicle accident is the most common cause over 10 years
    • correlated with age due to the increased thickness of the cortical shaft during skeletal growth and maturity
  • Associated conditions
    • high suspicion for child abuse required 
      • abuse must be considered if the child is < 3 years and especially if present in a patient before walking age
      • femur fractures are one of the most common fractures associated with child abuse
    • medical conditions and comorbidities
      • osteogenesis imperfecta 
      • osteopenia secondary to neuromuscular disorders
      • benign or malignant bone tumors
  • Prognosis
    • high rate of fracture union if appropriate treatment is selected based on patient age and fracture pattern
Anatomy
  • Osteology
    • anterior bow to femur
    • isthmus is the narrowest portion of the femur
  • Muscles
    • iliopsoas creates a flexion and external rotation force on the proximal fragment
    • adductors create a shortening and varus force on the distal fragment
  • Biomechanics
    • femoral shaft cortical diameter and cortical thickness increase with age 
Classification
  •  Descriptive classification
    • characteristics of the fracture
      • transverse
      • comminuted
      • spiral
      • Others
    • location of the fracture
      • proximal, middle, or distal third
    • integrity of the soft-tissue envelope
      • open vs closed fracture
  • Stability
    • stable fractures
      • typically transverse or short oblique
    • unstable fractures
      • long spiral (fracture length > 2 X bone diameter at that level) or comminuted fractures
Presentation
  • Symptoms
    • thigh pain
    • inability to walk
    • report of deformity or instability
  • Physical exam
    • gross deformity
    • shortening
    • swelling of the thigh
Imaging
  • Radiographs
    • AP and lateral of the femur
      • allow for complete evaluation of the fracture location, configuration, and amount of displacement
    • ipsilateral AP and lateral of knee and hip
      • to rule out associated injuries
Treatment
  • Nonoperative
    • Pavlik harness
      • indications
        • children up to 6 months
        • any fracture pattern
    • spica casting  
      • indications
        • children 0 - 5 years 
        • relatively contraindicated with polytrauma, open fractures and shortening > 2-3 cm
    • traction + delayed spica casting
      • indications
        • younger patients with significant shortening 
        • rarely utilized
  • Operative
    • flexible intramedullary nails 
      • indications
        • most length stable fracture patterns in children 5 - 11 years weighing < 49kg (100 lbs)
    • submuscular bridge plate fixation 
      • indications
        • unstable fractures in children 5 or older and >49kg (100lbs)   
        • very proximal or very distal fractures
        • severe comminution
    • antegrade rigid intramedullary nail fixation 
      • indications
        • in patients >11 years or approaching skeletal maturity
        • unstable fractures
        • fractures in patients weighing > 49kg (100 lbs)
    • external fixation  
      • indications
        • damage control orthopedics in a polytrauma patient  
        • open fractures 
        • associated vascular injuries requiring revascularization
        • segmental or significantly comminuted fractures
 
Treatment Table by Age
< 6 months
  • Any fracture pattern
  • Pavlik harness  
  • early spica casting
6m - 5 years
  • stable fracture pattern
  • early spica casting  
  • unstable fracture pattern
  • polytrauma/multiple fx/open fx
  • traction with delayed spica casting  
  • external fixator
5 - 11 years
  • length stable fx (transverse or oblique fx patterns)
  • patient weighs <  49kg (100 lbs)
  • flexible intramedullary nails   
  • length unstable fx (comminuted or spiral)
  • very proximal or distal fx
  • any weight
  • ORIF with submuscular bridge plating  
  • external fixation 

11 or greater years

 

  • patient weight <  49kg (100 lbs)
  • flexible intramedullary nails  
  • patient weight > 49kg (100 lbs)
  • antegrade rigid intramedullary nail fixation 
  • proximal or distal fracture
  • severe comminution
  • ORIF with submuscular bridge plating
Surgical Techniques
  • Pavlik harness
    • technique
      • avoids the need for sedation or anesthesia
    • complications
      • can compress femoral nerve if excessive hip flexion is used in presence of a swollen thigh
        • identified by decreased quadriceps function
  • Immediate spica casting  
    • technique
      • applied with reduction under sedation or with general anesthesia
      • single-leg spica or one-and-one-half spica (to control rotation)
        • distal femoral buckle fracture may be treated with long leg cast alone (not spica)
      • hips flexed 60-90° and approximately 30° of abduction
      • external rotation is typically needed to correct a rotational deformity
      • molded into recurvatum and valgus as the muscular forces will pull fracture into procurvatum and varus
      • molds along the distal femoral condyles and buttocks help to maintain reduction
      • acceptable limits are based on age
        • the goal of reduction should include obtaining < 10° of coronal plane and < 20° of sagittal plane deformity with no more than 2cm of shortening or 10° of rotational malalignment
      • a special car seat is sometimes needed for transport (often can use a regular car seat if single-leg spica is used)
    • complications
      • compartment syndrome
        • decreased with applying smooth contours around popliteal fossa, limiting knee flexion to < 90° and avoiding excessive traction
        • Decreased by avoiding applying short leg cast first followed by traction on poplitea fossa 
        • monitored for by observing the child's neurovascular exam and level of comfort
    • outcomes
      • healing times vary from 4 - 8 weeks based on age
  •  Traction + delayed spica casting
    • technique
      • placed in distal femur proximal to distal femoral physis
        • proximal tibial traction can cause recurvatum due to damage to the tibial tubercle apophysis  
      • used for 2-3 weeks to allow early callus formation
      • spica casting then applied until fracture healing
    • more complications than immediate spica casting
  • Flexible intramedullary nails 
    • approach
      • all distal approach
        • 2cm incision medially and laterally at level of distal physis
        • spread with hemostat to starting point 2cm proximal to physis
      • distal and proximal approach
        • 2cm incision laterally at level of distal physis and 2cm incision proximally at greater troch apophysis
    • instrumentation
      • nail size determined by multiplying the width of the isthmus of femoral canal by 0.4
      • the goal is 80% canal fill 
    • complications
      • the most common complication is pain at insertion site near the knee
        • in up to 40% of patients
        • recommended that < 25mm of nail protrusion and minimal bend of the nail outside the femur are present
      • increased rate of complications in patients 11 years or up or > 50 kg 
      • malunion
        • increased rates with comminuted, shortened, or very proximal/distal fractures
    • outcomes
      • generally good outcomes
      • time to union is typically 10 - 12 weeks
      • removal of the nail can be performed at 1 year
  • Submuscular bridge plate fixation 
    • approach
      • laterally based incision and plating with minimal disruption of soft tissue envelope
      • small proximal and distal incisions and plate is placed between periosteum and vastus lateralis on the lateral side of the femur
    • fracture is provisionally reduced with closed or percutaneous techniques
    • instrumentation
      • typically use 12-16 hole 4.5mm narrow LC-DC plate with 3 screws proximal and 3 screws distal to the fracture.  the plate may need to be bent to accommodate the natural bend of the femur
      • Contoured femur plates are also an option
    • complications
      • hardware removal
      • refracture following hardware removal
    • outcomes
      • favorable time to union, weight bearing, hardware irritation, and limp outcomes
  • Antegrade rigid intramedullary nail fixation 
    • approach
      • trochanteric entry nail
      • lateral entry nail
        • avoid piriformis entry due to risk of injury to vascularity to femoral head
    • soft tissue
      • lateral incision proximal to the greater trochanter
      • sharp or electrocautery through fascia lata to obtain starting point at the tip of the greater trochanter
    • closed versus open reduction of the fracture
    • instrumentation
      • with fracture reduced follow steps to insert intramedullary nail with caution to not cross distal physis
    • complications
      • osteonecrosis risk is 1-2% with piriformis start in a patient with open proximal physes
      • the exact risk of osteonecrosis with greater trochanter and lateral entry nails is unknown
      • secondary deformities of the proximal femur can occur after greater trochanteric insertions
        • narrowing of the femoral neck
        • premature fusion of greater trochanter apophysis
        • coxa valga
        • hip subluxation
    • outcomes
      • decreased risk of angular malunion
      • favorable outcomes in adolescents
  • External fixation  
    • technique
      • applied laterally
        • avoid disruption and scarring of quadriceps
      • 10 - 16 weeks of fixation is typically needed for solid union weight-bearing
      • weight-bearing as tolerated can be considered with stiff constructs
    • complications
      • more complications than internal fixation
      • pin tract infections are frequent
        • as high as 50% of fixator related complications
        • treated with oral antibiotics and pin site care
      • higher rates of delayed union, nonunion and malunion
      • increased risk of refracture (1.5-21%) after removal of fixator especially with varus malunion
Complications
  • Leg-Length Discrepancy 
    • overgrowth
      • the most common complication in younger patients
      • 0.7 - 2 cm is common in patients <10 years
      • typically occurs within 2 years of injury
    • shortening
      • is acceptable if less than 2 - 3 cm because of anticipated overgrowth in young patients
      • can be symptomatic if greater than 2 - 3 cm 
        • temporary traction or fixation used to prevent persistent shortening
  • Osteonecrosis (ON) of the femoral head  
    • reported with both piriformis and greater trochanter entry nails 
    • femoral nailing through the piriformis fossa is contraindicated in adolescents with open physes because of the risk of osteonecrosis of femoral head
    • main supply to femoral head is deep branch of the medial femoral circumflex artery 
      • branches into superior retinacular vessels that supply the femoral head 
      • vulnerable as it lies near the piriformis fossa  
  • Nonunion and malunion 
    • higher risk with load bearing devices
      • external fixator or submuscular plates
    • can occur after flexible intramedullary nailing in patients
      •  aged over 11 years old
      •  who weigh >49 kg (>108 lb)
    • the typical deformity is varus + flexion of the distal fragment
    • remodeling is greatest in the sagittal plane 
    • rotational malalignment does not remodel 
    • nearly 50% of fractures treated with flexible nails have 15 degrees of malalignment
  • Refracture
    • most common after external fixator removal with varus malalignment