2(1-Acetyl-2-oxopropylidene)naphtho[2,3-d][1,3]dithiole-4,9-dione 1 reacts with a variety of bidentates reagents to give some new functionally substituted spiro naphthodithiole-4,9-dione derivatives. إقراء المزيد

Tramadol hydrochloride (T), (±)-cis-2-[(dimethylamino)- methyl]-1-(3-methoxyphenyl)cyclohexanol (1) [1-7] is a centrally acting analgesic agent used in the treatment of moderate to severe pain and as an alternative to opiates [8]. The sensitive analysis for drugs of abuse in seized materials or biological fluids has become important for forensic and toxicological laboratories. High performance liquid chromatography (HPLC) with ultraviolet (UV) [9-13] is ... إقراء المزيد

An efficient one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones or thiones is described using ceric ammonium nitrate (CAN) as a catalyst in the reaction of an aromatic aldehyde, β-ketoester and urea or thiourea under solvent free conditions in terms of excellent yields and very short reaction time. [Eman A. Ahmed, Mounir A. A. Mohamed and Ahmed M. M. El-Saghier. One-Pot Synthesis of Dihydropyrimidin-2(1H)-ones ... إقراء المزيد

In the title compound, C13H13N3O3, the pyrazolidine ring adopts a shallow envelope conformation, with the carbonyl C atom closest to the benzene ring as the flap [deviation of 0.126 (1) A ˚ from the plane through the remaining atoms (r.m.s. deviation = 0.011 A ˚ )]. The dihedral angle between the pyrazolidine ring (all atoms) and the benzene ring is ... إقراء المزيد

In the title compound, C15H17N3O2, the dihedral angle between the planes of the pyrazolidine and phenyl rings is 29.91 (6). The piperidine ring adopts a chair conformation. In the crystal, molecules are linked into chains running parallel to the a-axis direction by a combination of N—H O and C—H O hydrogen bonds. Furthermore, there exist C—H interactions and – stacking ... إقراء المزيد