The aim of the study was to evaluate the association between the gene polymorphisms in interleukin-10 (IL-10) and interferon gamma (IFN-g) genes with susceptibility and severity of hepatitis C virus (HCV) infection among Egyptian patients. Interleukin-10 -592 A/C, -1082 G/A and IFN-g +874 T/A genotypes were determined in 100 chronic HCV patients and 50 healthy controls using restriction fragment length ... Read more

Background: Gram-negative bacteria; such as Escherichia, Klebsiella, Enterobacter, proteus, Pseudomonas and Acinetobacter, are common human pathogens. Now, it is difficult to treat these infections by most of the available antibiotics due to emergence of multidrug resistant Gram-negative bacilli or Red Plague. Objectives: This work aims to identify the rate of resistant gram negative bacteria in Sohag University hospital. Methodology: The ... Read more

ABSTRACT Treponema pallidum is a motile Gram-negative bacterium causing syphilis. Syphilis is one of the known sexually transmitted infections (STIs) and transfusion transmitted infections (TTIs). Blood samples from 16,000 Egyptian blood donors attending all blood banks in Suhag governorate during the period between January 2015 to December 2015 were screened for markers of infection with hepatitis B virus (HBV), hepatitis ... Read more

Background: Extended-spectrum β-lactamases (ESBLs) production is the major resistance mechanism to β-lactam antibiotics in Enterobacteriaceae. Moreover, the emergence of quinolone resistance in ESBLs-producing isolates had become a global threat for treatment of infections caused by these bacteria. Objectives: We investigated the association between ESBLs production and quinolone resistance in Klebsiella pneumoniae isolates. Methodology: A total of 148 isolates of K. ... Read more

Background: Infection with herpes simplex virus is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn, which can lead to death or long-term disabilities. Objectives: The aim of our study was to detect the seroprevalence of Herpes ... Read more