Background Pityriasis rosea (PR) is an acute, self-limiting papulosquamous skin disease. T-helper lymphocytes play an important role in the pathogenesis of PR. However, the role of cytotoxic T-lymphocytes is poorly understood. Objective To investigate the immune profile of mixed inflammatory cell infiltrate in skin lesions with PR. Methods The study included 10 biopsy specimens from lesional skin with clinical diagnosis ... Read more

BACKGROUND: Pityriasis rosea is an acute, self-limiting papulosquamous skin disease .T-helper lymphocytes play an important role in the pathogenesis of PR. However, the role of cytotoxic T-lymphocytes is poorly understood. OBJECTIVE: To investigate the immune profile of mixed inflammatory cell infiltrate in skin lesions with PR. METHODS: The study included 10 biopsy specimens from lesional skin with clinical diagnosis of ... Read more

Background: Skin diseases form a major part of the total spectrum of health problems. The type and distribution of skin diseases in any community reflects genetic constitution, nutritional status, social and hygienic standards, customs and occupations. The objective of this study was to investigate the pattern of distribution of skin diseases in a rural area from Upper Egypt, and its ... Read more

OBJECTIVES: To compare the expression of Bcl-xl (antiapoptotic) and Bax (proapoptotic) factors in psoriatic patients treated with calcipotriol alone with those treated with combination of calcipotriol and mometasone furoate, also to compare the expression of these factors in keratinocytes of lesional with non lesional skin of psoriatic patients and of controls, and lastly to correlate the level of these parameters ... Read more

_Ba__c__k__g__r__o__und_ Pityriasis rosea (PR) is an acute, self-limiting papulosquamous skin disease. T-helper lymphocytes play an important role in the pathogenesis of PR. However, the role of cytotoxic T lymphocytes is poorly understood. _Obj__ec__ti__ve_ To investigate the immune profile of mixed inflammatory cell infiltrate in skin lesions with PR _M__e__thod__s_ The study included l 0 biopsy specimens from lesional skin with ... Read more

Background: Nerve growth factor (NGF) and its high-affinity recep- tor, tyrosine kinase A (TrkA), are members of the neurotrophin family. NGF–TrkA are involved in murine hair morphogenesis and cycling. To date, their expression in human hair follicle (HF) is unknown. In this investigation, we hypothesize that NGF–TrkA proteins are expressed in the human scalp skin. Moreover, NGF–TrkA expression in HF ... Read more

This is an observational descriptive study conducted upon three primary school pupils in Sohag Governorate. The idea was to estimate the incidence and the epidemiological factors related to Pediculosis capitis infestation amongst the selected population. It has been found that the infestation affected about 16 % of the whole group. Rural pupils were more frequently, albeit insignificantly, infested (17.44 versus ... Read more

Introduction: Data about sexual dysfunction (SD), particularly erectile dysfunction (ED), in patients with chronic hepatitis B and C remain unclear and insufficient. Aim: To determine sexual problems particularly (ED) in patients with chronic hepatitis B and C, study changes in sex hormones and liver functions in chronic hepatitis patients with and without sexual problems and correlate sexual problems with other ... Read more

BACKGROUND Neurotrophin (NT)‐3 and its high‐affinity receptor tyrosine kinase C (Trk C) are essential for nervous system development. These members of the NT family are also involved in murine hair morphogenesis and cycling. However, their role in human hair follicle (HF) biology remains to be elucidated. OBJECTIVES To explore the role of NTs in human skin and HF biology. METHODS ... Read more

OBJECTIVE: To assess the types, distributions, and numbers of immune cell infiltrates in the testes of men with azoospermia. DESIGN: Prospective study. SETTING: University research and clinical institutes. PATIENT(S): Thirty-one men with azoospermia showing normal spermatogenesis (n=10), germ cell maturation arrest (GA, n=12), and Sertoli cell– only syndrome (SCO, n=9). INTERVENTION(S): Testicular tissue biopsies. Sections were stained with routine (hematoxyline ... Read more