Human scalp skin and hair follicles express neurotophin-3 and its high- affinity receptor tyrosine kinase C, and show hair cycle-dependent alterations in expression.
BACKGROUND Neurotrophin (NT)‐3 and its high‐affinity receptor tyrosine kinase C (Trk C) are essential for nervous system development. These members of the NT family are also involved in murine hair morphogenesis and cycling. However, their role in human hair follicle (HF) biology remains to be elucidated. OBJECTIVES To explore the role of NTs in human skin and HF biology. METHODS ... Read more