* BACKGROUND: Chronic radio dermatitis is a frequent side effect of radiotherapy. It may be associated with decreased quality of life. AIMS: The aim of this study was to evaluate the clinical efficacy and safety of intralesional injection of triamcinolone acetonide for the treatment of patients with chronic radio dermatitis. METHODS: This study was a prospective clinical trial conducted on ... Read more

Background: Acne vulgaris is the most common dermatological condition encoun- tered in adolescents. Aim: It was to determine the prevalence of acne vulgaris and its impact of the quality of life among adolescents attending secondary schools in Sohag Province, Upper Egypt. Patients and methods: This was a cross-sectional study conducted in randomly selected governmental and technical secondary schools in Sohag ... Read more

Alopecia areata is a common cause of nonscarring alopecia that occurs in a patchy, confluent, or diffuse pattern. Dermoscopy is a noninvasive technique for the clinical diagnosis of many skin diseases. Topical minoxidil solution 5% and platelet rich plasma are important modalities used in treatment of alopecia areata. We aimed to evaluate the efficacy of PRP versus topical minoxidil 5% ... Read more

Background Etiopathogenesis of vitiligo is unclear. Immunological background has a role.Interleukin 17 (IL-17) may play a role in its pathogenesis. There is no standard treatment regimen for vitiligo; however, calcineurin inhibitors may be an effective treatment option. Objective The aim was to evaluate tacrolimus versus narrowband ultraviolet B (NB-UVB) intreatment of vitiligo, both clinically and by measurement of IL-17 before ... Read more

Background Dermoscopy is a simple and inexpensive diagnostic technique that permits the visualization of morphologic features that are not visible to the naked eye, forming a link between clinical dermatology and microscopic dermatopathology. For many years, skin biopsy was considered the only definite diagnostic tool that confirms or excludes the clinical diagnosis. Skin biopsies are invasive and have many adverse ... Read more

INTRODUCTION & OBJECTIVES Chronic renal failure (CRF) is a progressive loss in renal function over a period of months or years. It is differentiated from acute kidney disease in that the reduction in kidney function must be present for over 3 months. In Egypt; end stage renal disease (ESRD) is growing by 100% annually; the estimated annual incidence of ESRD ... Read more

INTRODUCTION & OBJECTIVES Vitiligo is a common disease with an immunological background. There is no standard treatment regimen for vitiligo. Interleukin 17 (IL-17) may play a role in pathogenesis of vitiligo. Evaluation of Tacrolimus and Narrow band UVB (NB-UVB) in treatment of vitiligo both clinically and by measurement of IL-17 before and after treatment. MATERIALS & METHODS 45 patients with ... Read more

BACKGROUND: Chronic renal failure or chronic renal disease (CRD) is a progressive oss in renal function over a period of months or years. It is differentiated from acute kidney disease in that the reduction in kidney function must be present for over 3 months Uremic pruritus is the most common cutaneous abnormality in patients with CRF Uraemic pruritus is unrelated ... Read more

INTRODUCTION & OBJECTIVES Cutaneous Warts (CW) or verrucae are benign proliferation of skin that result from infection with human papilloma viruses. Cellular immune reactivity plays a significant role in wart regression. To elucidate the cellular immune status of patients with CW through measurements of their serum levels of Interleukin-17 (IL-17) and Macrophage Migration Inhibitory Factor (MIF), hence, identify the possible ... Read more

Background: Melasma is a common dyschromia that often motivates the search for dermatological care as it results in cosmetic disfigurement that impairs the patient’s quality of life. Aim: To evaluate the effect of microneedling with addition of topical vitamin c in treatment of melasma. Materials and Methods: This is a prospective study that included 34 adult females with 4 dropouts. ... Read more