Introduction: Acne scarring is a common undesirable complication of acne vulgaris. Fractional erbium-yttrium aluminum garnet (YAG) 2940 nm laser and platelet-rich plasmahave been used in treating acne scars with variable outcomes. The objective of this study is to assess the efficacy of fractional erbium-YAG 2940 nm laser and platelet-rich plasma as single line of treatment in comparison with combined treatment ... Read more

Introduction: Leptin is a 167 - amino acid polypeptide hormone, identified in 1994 by positional cloning in the mouse and human. This hormone is secreted by the white adipose tissue in proportion to body energy (fat) stored. Leptin functions as a satiety factor in the regulation of body weight. So far, many studies have pointed to a direct role of ... Read more

Background: Pruritus is a distressing symptom of cholestatic, inflammatory,and malignant liver diseases. It is a common symptom in many biliary andcholestatic disorders such as primary biliary cirrhosis (PBC). Several mechanisms are generally accepted as possible explanations to the underlying basis of itch.However, the exact pathophysiology of pruritus in liver diseases remains unclear.The cutaneous and central neurobiology of pruritus is complex ... Read more

Male androgenetic alopecia (AGA) is the most common type of hair loss in men. It accounts for more than 90% of all cases of alopecia in men (1>. It occurs when genetically predisposed men are exposed to androgens. AGA may negatively affect patient's quality of life and can lead to social and job-related problems (21. AGA can also cause indirect ... Read more

Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae and manifested by an immunological and clinical outcome, ranging from borderline lepromatous and lepromatous infections to tuberculoid and borderline tuberculoid infections. Cytokines such as interleukin (IL)-6, IL-10, interferon-γ (IFN-γ), and tumor necrosis factor-α are associated with leprosy. Objective The aim was to assess IL-6 and IFN-γ in untreated patients ... Read more

Background: Cirrhosis often is a silent disease Clinical symptoms at presentation may include jaundice of the eyes or skin, pruritus, gastrointestinal bleeding, coagulopathy, increasing abdominal girth, and mental status changes. Pruritus may be the presenting symptom, arising years before any other classic clinical and laboratory markers of hepatic dysfunction. This study examines the clinical, laboratory and histopathological changes in the ... Read more

Introduction: Microneedling is a relatively new minimally invasive procedure involving superficial and controlled puncturing of the skin by rolling with miniature fine needles. Traditionally used as a collagen induction therapy for skin rejuvenation and facial scars specially acne scars. Aim of the work: Evaluation of efficacy of microneedling in treatment of acne scars. Patients and Methods: Ten patients with post ... Read more

Androgenetic alopecia (AGA) is the result of progressive, patterned hair loss that occurs when genetically predisposed individuals are exposed to androgens. The psychosocial impact of AGA may negatively affect patient's quality of life and can lead to personal social and job• related problems (I). Also; AGA can cause indirect physical harm to some patients, such as sunburn as a result ... Read more

Introduction: Acne scars are largely preventable complications of acne. 95% of the scars occur over the face thus impacting the quality of life. Correction of scars is the priority for acne patients. There is no single treatment modality that has been shown to be universally effective. Microneedling is a relatively new minimally invasive procedure used as a collagen induction therapy ... Read more

Vitiligo is an acquired autoimmune depigmentation of the skin, affecting 2%of the population with great impact on quality of life, which is more devastating in people with skin of color. The most important selection criterion in vitiligo for considering melanocyte keratinocyte transplantation procedure (MKTP) is stability. However, there is no consensus regarding the required period to define clinical stability. Moreover, ... Read more