eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

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  • Courses 28
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Chronic adenosine receptor blockade with BG9928 attenuates cardiac and renal histopathology and improves diabetes in animals with the metabolic syndrome

2008 | Keywords Diabetes , renal histopathology, Cardiac, adenosine receptor blockade,
Chronic adenosine receptor blockade with BG9928 attenuates cardiac and renal histopathology and improves diabetes in animals with the metabolic syndrome
PURPOSE: In animals and patients with left ventricular dysfunction, shortterm A1 adenosine receptor blockade causes diuresis/natriuresis without altering potassium excretion and, in contrast to loop diuretics, improves renal function. Blockade of the A2b adenosine receptor has an antidiabetic effect. The purpose of this study was to examine the long-term efficacy and safety of BG9928, a novel, orally active, and highly ... Read more

Renal and metabolic effects of tempol in obese ZSF1 rats--distinct role for superoxide and hydrogen peroxide in diabetic renal injury

2008 | Keywords diabetic renal,
Renal and metabolic effects of tempol in obese ZSF1 rats--distinct role for superoxide and hydrogen peroxide in diabetic renal injury
Oxidative stress, that is, overproduction of reactive oxygen species and reduced antioxidant system activity, is implicated in the pathogenesis of diabetic complications; and therefore, superoxide dismutase (SOD) mimetic tempol should be protective in diabetic kidney. However, the effects of tempol in metabolic syndrome-associated renal injury have not been thoroughly examined. In this study, we examined the effects of 9 weeks ... Read more

Role of Survivin in Glioma Progression: A Clinico-Pathological Study

2007 | Keywords Survivin, Glioma,
Role of Survivin in Glioma Progression: A Clinico-Pathological Study
ABSTRACT OBJECT: Gliomas are among the most aggressive of all human malignancies. Glioblastoma multiforme is the most malignant histo-pathological subtype. Survivin is one of the inhibitors of apoptosis. It is over-expressed in many human cancers. We performed clinical and pathological study aimed to clarify its role in glioma progression. METHODS: This study included 34 glioma patients. Clinical evaluation including age, ... Read more

Secular trend is not only accused for the increased incidence of PET, but also for its severity

2007 | Keywords its severity, PET, Secular trend,
Secular trend is not only accused for the increased incidence of PET, but also for its severity
ABSTRACT OBJECTIVE: To determine the role of secular trend in preeclampsia. MATERIALS AND METHODS: Both at puberty and in the 3rd trimester of 65 singleton-primigravid preeclapmtics (Group I) and 867 comparable healthy, pregnants (Group II), body mass index (BMI), serum testosterones (total & free), dehydroepiandrosterone sulfate, estradiol and sex hormone-binding globulin levels were measured. Also, the ages at menarche, umbilical ... Read more

Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats

2007 | Keywords Renal injury, caffeine, obese, Diabetes , ZSF1 rats,
Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats
ABSTRACT: Our previous studies indicate that prolonged caffeine consumption exacerbates renal failure in nephropathy associated with the metabolic syndrome. Reduced activity of the antioxidant defense system and beneficial effects of antioxidant therapy have been reported in diabetic rats and humans. The purpose of this study was to examine the early renal effects of caffeine consumption and the effects of concomitant ... Read more

Celiac Disease, TB enterocolitis, and Giardiasis among Children with Chronic Diarrhea: The Accuracy of ANT-EMA AND tTG Expression in the Diagnosis of Celiac Disease

2006 | Keywords Celiac Disease, Chronic Diarrhea,
Celiac Disease, TB enterocolitis, and Giardiasis among Children with Chronic Diarrhea: The Accuracy of ANT-EMA AND tTG Expression in the Diagnosis of Celiac Disease
BACKGROUND: Chronic diarrhea is one of the most common causes of referral to a gastroenterology clinic. Chronic diarrhea may result from many different causes; celiac disease is one of them. Other important causes in our locality are infections such as TB and Giardiasis. AIM OF THE WORK: This work was planned to: 1- Determine the frequency of celiac disease, TB ... Read more

Facial nerve dysfunction following conservative primary parotid surgery

2006 | Keywords primary parotid surgery, dysfunction, Facial nerve,
Facial nerve dysfunction following conservative primary parotid surgery
AIM: The aim of this study is to analyse the incidence and highlight the risk factors associated with facial nerve dysfunction after conservative primary parotidectomy METHODS: The study included 41 patients, who were initially with normal facial nerve function and had been treated by conservative primary parotidectomy (42 procedures) for parotid neoplasms in Sohag University Hospital, during the period from ... Read more

Inflammatory bowel diseases: Diagnostic and therapeutic modalities

2006 | Keywords Inflammatory bowel diseases, Diagnostic, therapeutic modalities,
Inflammatory bowel diseases: Diagnostic and therapeutic modalities
BACKGROUND: Inflammatory bowel disease (IBD) is chronic conditions of unknown origin that result from continuous or intermittent inflammation of a part of the intestinal wall. The main classic types of IBD are ulcerative colitis (UC), Crohn's disease (CD) and indeterminate colitis that cannot be classified accurately as UC or CD with pure colonic involvement. The aim of this study is ... Read more

Immunohistochemical Analysis of the Immune Cells in Bilharzial Granuloma of the Urinary Bladder

2006 | Keywords Urinary Bladder, Bilharzial Granuloma, Immune Cells, Immunohistochemistry,
Immunohistochemical Analysis of the Immune Cells in Bilharzial Granuloma of the Urinary Bladder
ABSTRACT BACKGROUND: URINARY BILHARZIASIS REPRESENT A MAJOR HEALTH PROBLEM IN EGYPT. IT IS CHARACTRARIZED BY THE FORMATION OF LOCALIZED COLLECTION OF IMMUNE CELLS I.E. GRANULOMAS. IN THIS INVESTIGATION, WE HYPOTHESIZED THAT THE EVOLUTION OF THE BILHARZIAL GRANULOMA IS ASSOCIATED WITH RECRUITMENT OF IMMUNE CELLS OF DIVERSE CELL LINEAGE. TO EXPLORE THIS HYPOTHESIS AND TO FILL THIS EXISTING GAP IN THE ... Read more

Expression of apoptosis-regulating proteins p53, and bax in primary resected esophageal squamous cell carcinoma

2006 | Keywords Apoptosis, esophagealus, Esophagus, P53, Bax, squamous cell carcinoma,
Expression of apoptosis-regulating proteins p53, and bax in primary resected esophageal squamous cell carcinoma
ABSTRACT Currently, clinico-pathological staging and classification of residual tumor are the most important prognostic factors for clinical outcome in esophageal cancer. Nevertheless, patients with similar stages of the disease show a marked discrepancy in survival. Several new molecular prognostic factors are being evaluated in the hope that they may contribute to better assessment of the survival probability and, consequently, the ... Read more