Mahmoud Saif Al-Islam Abd Elfatah

استاذ مساعد - استاذ مساعد طب المناطق الحارة والجهاز الهضمي

كلية الطب

العنوان: كلية الطب قسم طب المناطق الحارة والجهاز الهضمي


2018 | الكلمات المفتاحية (Hepatocellular carcinoma (HCC, Egypt, Risk factors,
Hepatocellular Carcinoma in Upper Egypt: A Retrospective Study
Abstract Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths worldwide. The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B and hepatitis C strongly predisposes to the development of chronic liver disease and subsequent development of HCC. Aim of the Work: Our study was designed to characterize ... إقراء المزيد

2017 | الكلمات المفتاحية APRI, FIB-4, Fibrosis, hepatitis C infection,
Evaluation of Aspartate Aminotransferase Platelets Ratio Index (APRI) and FIB-4 as Non Invasive Predictors of Hepatic Fibrosis in Patients with Chronic Hepatitis C *
Abstract Objectives: This study aims to assess simple models from routine investigation for prediction of significant fibrosis (Ishak score > 2) and cirrhosis in CHC patients. Patients and Method: Our retrospective cohort study studied 100 chronic HCV patients that had liver biopsy. Two indices were assessed, aspartate aminotransferase platelets ratio index (APRI) and FIB-4 to predict significant fibrosis and cirrhosis. ... إقراء المزيد

2016 | الكلمات المفتاحية Pegylated Interferon, Ribavirin Therapy, hepatitis C virus, oral ribavirin,
Hematological Side Effects of Pegylated Interferon/ Ribavirin Therapy   in Chronic HCV Egyptian Patients
Hepatitis C virus (HCV) infection is a major health problem throughout the World. Egypt has the highest worldwide prevalence of HCV (10-20%). The combination of peginterferon and ribavirin can achieve sustained virologic response in over 50% of those treated. However, adherence to treatment is critical to maintain high rates of virologic clearance. Unfortunately, peginterferon plus ribavirin therapy can be associated ... إقراء المزيد

Role of Serum Zinc Level and P300 Event Related Potential in Detection of Minimal Hepatic Encephalopathy
Background: Minimal hepatic encephalopathy (MHE) is defined as hepatic encephalopathy (HE) without symptoms on clinical/neurological examination, but with deficits in some cognitive areas that can only be measured by neuropsychometric testing. Aim: Our aim was to study serum zinc levels in cirrhotic patients with and without MHE and correlate it with the results of neuropsychological tests and P300 event related ... إقراء المزيد

2015 | الكلمات المفتاحية Atherosclerosis, Ischemic stroke, HCV,
Characteristics of ischemic stroke in asymptomatic hepatitis C virus positive patients
Abstract: Background and aim of the study: Cerebrovascular diseases are leading cause of death worldwide. Acute ischemic cerebrovascular events, including ischemic stroke (IS) , transient ischemic attack, and lacunar syndromes, have been reported in hepatitis C virus infected patients. Various surveys were designed to study the associations and pathophysiology of ischemic stroke in patients with hepatitis C virus infected patients. ... إقراء المزيد

Helicobacter pylori infection in women with non-menstrual migraine without aura. A case-control study
ABSTRACT _BACKGROUND AND AIM OF THE STUDY:__ In the last 2 decades, a relation between Helicobacter pylori (HP) chronic infection and migraine has been studied but the results of these studies are controversial. The aim of this study was to determine whether current or previous exposure to HP infection is a risk factor in women with non-menstrual migraine without aura, ... إقراء المزيد

2015 | الكلمات المفتاحية CHC, BMI, adiponectin, tumor necrotic factor-α, homeostasis model of assessmen,
Metabolic Factors Associated with Hepatic Steatosis and Fibrosis in Chronic Hepatitis C Patients
_ABSTRACT_ OBJECTIVE: Hepatic steatosis is a common histological feature in chronic hepatitis C (CHC), but its pathogenic mechanisms are not completely understood. We aimed to evaluate the metabolic factors associated with hepatic steatosis and fibrosis in CHC patients, and the relation between metabolic syndrome (MS) and CHC. PATIENTS AND METHODS: This study included 71 patients with CHC infection who underwent ... إقراء المزيد

Gastroesophageal Reflux Disease in Patients with Minimal Associated Pathological Lesions of the Vocal Folds with Associated Symptoms and Laryngeal Findings
Abstract: The purpose of this current study is to investigate the role of gastroesophageal reflux disease (GERD) as a risk factor for Minimal Associated Pathological Lesions (MAPLs) of the vocal folds with associated symptoms and laryngeal findings, and to assess the prevalence of GERD in these patients. This study included one hundred and fourteen patients with MAPLs and associated symptoms ... إقراء المزيد

2013 | الكلمات المفتاحية Hepatic decompensation, hepatitis, liver cirrhosis, outcome, Risk factors,
Prognosis and determinants of pregnancy outcome among patients with post-hepatitis liver cirrhosis
Objective: To evaluate maternal, fetal, and neonatal outcomes and their associated risk factors among pregnant women with liver cirrhosis (LC). Methods: A prospective cohort study was conducted at Sohag University Hospital, Egypt, between May 1, 2009, and April 1, 2012. Participants included 129 pregnant women with LC (study group), 647 pregnant women without LC (control group 1), and 853 non-pregnant ... إقراء المزيد

2013 | الكلمات المفتاحية Chronic Hepatitis C, hepatitis grade and stage, alanine transaminase,
Correlation of Serum Alanine Transaminase Level and Virus Load to the Extent of Liver Damage in Patients with Chronic Hepatitis C
Introduction: Hepatitis C virus (HCV) infection is usually monitored by the level of alanine transaminase (ALT) and viral load. However, accumulating data indicate that these parameters are not always correlated with the disease progression. Aim of the Work: This study aims to evaluate the relationship between serum ALT, serum HCV-RNA titer and the degree of histopathological liver damage in patients ... إقراء المزيد