The results of radiotherapy alone in patients with locally advanced nasopharyngeal carcinoma (NPC) were disappointing. Cisplatin-based concomitant chemoradiotherapy (CCRT) has demonstrated higher rates of local control and significantly reduced distant metastasis than radiotherapy (RT) alone in patients with locally advanced NPC. In view of the high rate of severe mucosal and bone marrow toxicities reported with the high doses of ...
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