Review of Role of Platelet Rich Plasma in Vitiligo.
Vitiligoisadisfiguringdiseaseaffectingskinandmucousmembranes causingsocialstigma.CharacterisedbyMilkyWhitepatches,duetoloss ofmelanocytes.Itremainsunclearwhatcausesdamageordeathtothe melanocytes,therearemanypotentialpathophysiologicaltheories involvingautoimmune,neural,autocytotoxic,biochemical,oxidative stress,melanocytorrhagy,anddecreasedmelanocytesurvival hypotheses. Theexactmechanism ofactionofPRPinvitiligoisstillunknown.The beneficialeffectofPRPinvitiligocouldbesuggestedthroughthese growthfactorswhichstimulatekeratinocytesandfibroblastsproliferation withsubsequentimprovementoftheirinteractionwithmelanocytes leadingtothestabilizationofmelanocytes. 2 Conclusion Vitiligoisacommondistressingdiseasewithsocialandpsychological effects,newmodalitiesoftreatmenthavebeenintroducedwithpromising effectofPRP,combinedwithothertreatments Read more