In this report, we presented a 67-year-old male patient complaining of discomfort and slight eye redness for 1 week in the right eye. His surgical history was notable for uneventful phacoemulsification with a posterior chamber intraocular lens implantation in this eye 3 years earlier. Slit-lamp examination of the same eye revealed an area of localized partial Descemet's membrane detachment (DMD) in the right eye. The detached membrane was rolled and wrinkled with no associated stromal edema with clear corneal stroma. Anterior segment optical coherence tomography showed incomplete detachment with no associated increase in the corneal thickness in areas overlying detached and attached DM. The decision was to proceed with conservative treatment with monthly follow-up. After 6 months, the condition remained stable with no change in size of the DMD or in the corneal clarity.