An alternative sequence of bioactive series, using novel Schiff base derivative (1-Quinolin-8-yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar conductivity, magnetic moment, IR, 1H NMR, UV-Vis, and TGA were used to define the chemical forms. As a result, an appropriate geometry has been proposed for each complex. The HNQ ligand functions as a tri-dentate via NNO donors to the metal ions within octahedral geometry with Cr3+, square pyramidal with VO2+, tetrahedral with Zn2+, and square planner with Pd2+ ion.