Abstract
Background: Obesity is a risk factor for obesity-related disorders such as type 2
diabetes mellitus. That obesity could hinder the individual work capacity and the cost
for managing obesity complications. Aim of Work: was to study the effect of diet
induced obesity and swimming on the plasma glucose, insulin, insulin resistance, body
mass index (BMI), muscle mass and muscle glycogen, and fat tissue weight according to
meal timing. Materials and Methods: Sixty Sprague dawely adult rats were
randomized into two equal groups control group and obese group. The first was exposed
for induction of obesity by hyper caloric diet and the other completes the standard one.
At the end of the 12th week of age, rats started the exercise program for three months.
The immediate group receives their meals immediately after exercise and the delayed
one receive their meals three hours later. Then after receiving their meal, free access to
food was allowed. Samples of blood were taken from all animals at the beginning and at
the end of experiment and examined for plasma glucose and plasma insulin. Insulin
resistance was estimated by HOMA-IR formula. Results: Immediate feeding after the
exercise bout produced greater increase in muscle bulk and muscle glycogen, with
decreased fat tissue weight in comparison with that of the corresponding delayed feeding
either on obese and control groups Conclusion: Immediate meal timing was a powerful
strategy to improve glucose homeostasis. Data of the present study showed that muscle
bulk was greater with lower fat tissue weight in the immediate feeding group versus the
delayed one.