The goal of present study is to determine whether metals or
nanomaterials are transferred from exposed pregnant females of viviparous
fishes to their developing offspring and the subsequent potential effects on
the oxidative stress and histomorphological indicators. Gravid females of
guppies (Poecilia reticulata) exposed to 1 mg/l copper sulfate (CuSO4) or
copper oxide nanoparticles (CuO-NPs) for 17 to 25 days depending on
giving birth. Once a female gave birth, the female and her newborn
offspring were analyzed for copper concentrations while some oxidative
stress parameters and histopathology were performed for the newborn
offspring. There were no malformations or histopathological lesions
observed in the newborn offspring of guppies exposed for either CuSO4 or
CuO-NPs. Also, there was no maternal metal transfer for either CuSO4 or
CuO-NPs while females exposed to copper sulfate only showed
significantly higher concentrations of Cu compared to control group. In
addition, there were non-significant changes in catalase compared to
control group. While, glutathione decreased significantly in offspring their
mothers exposed to CuO-NPs only compared to control group. In addition,
superoxide radical and lipid peroxidation increased significantly in
offspring their mothers exposed to CuSO4only compared to control group.
The findings of the present study indicated that the offspring were
more sensitive to CuSO4 than CuO-NPs. Although absence of metal Cu in
the tissues of offspring as well as lack of morphological abnormalities and
histopathology, maternal transfer of Cu metabolites may be suggested to
be the causative factor for some oxidative stress.