In this study two novel marine fungal isolates (Aspergillus oryzae and Fsarium solani) were used for
generating silver nanoparticles (SNPs). The antibacterial effect of mycological synthesized SNPs
(12.31±0.26 and 22.6 ±1.2nm for
A. oryzae and F. solani, respectively) was tested against Grampositive (Bacillus cereus SBTBC, Enterococcus faecalis 8J, Lesteria monocytogenes 10403S and
Staphylococcus aureus 7A) and Gram-negative bacteria (Escherichia coli and Salmonilla sp.). Silver
NPs exhibited higher bactericidal effect on the Gram-negative strains compared to the Gram-positive
ones. The minimum bactericidal concentration for
Bacillus cereus SBTBC, Enterococcus faecalis 8J,
Escherichia coli and Salmonilla sp. were 6.67, 6.67, 1.67 and 1.67 mg/mL, respectively, for synthesized
SNPs by
A. oryzae filtrate. And, 6.67, 13.33, 3.33 and 3.33 mg/mL respectively, for synthesized SNPs
F. solani filtrate against the same bacterial strains. Our results show that mycological synthesized
SNPs are promising compounds as antibacterial agents, however the exact mechanism of their
bactericidal effect needs to be elucidated, and the safety of using them commercially still need to be
more confirmed.