Vulvar cancer is an uncommon gynecological malignancy primarily affecting
postmenopausal women. There is no specific screening and the most effective strategy
to reduce vulvar cancer incidence is the opportune treatment of predisposing and
preneoplastic lesions associated with its development. While vulvar cancer may be
asymptomatic, most women present with vulvar pruritus or pain, or have noticed a
lump or ulcer. Therefore, any suspicious vulvar lesion should be biopsied to exclude
invasion. Once established, the most common subtype is squamous cell carcinoma.
Treatment of vulvar cancer depends primarily on histology and surgical staging.
Treatment is predominantly surgical, particularly for squamous cell carcinoma, although
concurrent chemoradiation is an effective alternative, particularly for advanced tumors.
Management should be individualized, and carried out by a multidisciplinary
team in a cancer center experienced in the treatment of these tumors.