Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط


2020 | Keywords FNAC, Thyroid Lesions,
Evaluation of Thyroid Lesions Using Fine Needle Aspiration Cytology
Background: Discrete thyroid swelling is common clinical presentation with prevalence rate of 4-7% in the general population. Now fine needle aspirate cytology (FNAC) is very important technique fordiagnosis of thyroid nodules, as it is very simple, safe, less invasive technique.Objective:To evaluate the diagnostic accuracy ofFNAC inThyroid Nodules.Patients and Methods:Study carried out on patients who visited the Outpatient Clinic of General ... Read more

2020 | Keywords Membranous Nephropathy, Phosph,
Detection of Phospholipase A2 Receptor Related Membranous Nephropathy in Membranous Nephropathy Patient.
Background: Membranous glomerulonephritis (MGN) considered as the most common causes of nephrotic syndrome (NS) in the world. Eighty percent of cases are classified as primary MGN. Primary MGN is an autoimmune disease in which autoantibodies against podocyte antigens forming subepithelial immune deposits and result in NS. Autoantibodies against M-type phospholipase A2 receptor (PLA2R) were found in 70-80% of patients with ... Read more

2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury
Estradiol may antagonize the adverse cardiovascular effects of angiotensin II (Ang II). We investigated the effects of 2-methoxyestradiol (2-ME), a nonestrogenic estradiol metabolite, on Ang II-induced cardiovascular and renal injury in male rats. First, we determined the effects of 2-ME on Ang II-induced acute changes in blood pressure, renal hemodynamics, and excretory function. Next, we investigated the effects of 2-ME ... Read more

2019 | Keywords Nestin, gliomas, stem cell,
Immunohistochemical expression of Nestin as Cancer Stem Cell Marker in gliomas
Background: Gliomas represent the most frequent primary tumors of central nervous system (CNS), contributing to more than half of the incidence of brain tumors. Cancer stem cell markers (CSC) identify a group of patients at high risk for progression. Nestin is an intermediate filament (IF) protein was first described as a neural stem cell/progenitor cell marker. Nestin-positive neuroepithelial stem cells ... Read more

2019 | Keywords Cytology, pleural effusion,
A Comparative Study of Conventional Cytology and Cellblock Method in Diagnosis of Pleural Effusion and their Correlation with Clinicopathological and Radiological Diagnosis
Background: Cytological Smear (CS) is extremely useful in patients with pleural effusions especially when malignancy is suspected. Cellblock (CB) technique is another method for examination of pleural fluid. In this study we aimed to compare the diagnostic yields of CS and CB technique and the combi-nation of both, regardless of the etiology of Pleural Effusion (PE), and to compare their ... Read more

2019 | Keywords Vitamin C, Aspartame, testes,
Protective Effect of vitamin C against Aspartame Toxicity to the Testes: A review article
Background: Aspartame is one of the most widely used artificial sweeteners.Aspartame has been shown to induce oxidative stress and lipid peroxidation; most serious effects result from chronic exposure due to these effects. Also it shows organ and species toxicity with relation to the liver, kidney, brain, testis and other organs.The aim of this study is to spotlight on aspartame hazards ... Read more

2019 | Keywords Aspartame, Toxicologists,
Aspartame: Basic Information for Toxicologists
Background: Aspartame is one of the most widely used artificial sweeteners in over 90 countries worldwide in over 6000 products, including carbonated and powdered soft drinks, hot chocolate, chewing gum, candy, desserts, yogurt, and tabletop sweeteners, as well as some pharmaceutical products like vitamins and sugar-free cough drops. Aspartame has been shown to induce oxidative stress and lipid peroxidation; most ... Read more

Captopril Attenuates Cardiovascular and Renal Disease in a Rat Model of Heart Failure With Preserved Ejection Fraction
نبذة مختصرة Heart failure with preserved ejection fraction (HFpEF), a prevalent form of heart failure, is frequently accompanied by the metabolic syndrome and kidney disease. Because current treatment options of HFpEF are limited, evaluation of therapies in experimental models of HFpEF with the metabolic syndrome and kidney disease is needed. In this study, we evaluated the effects of captopril, furosemide, ... Read more

2018 | Keywords stem cell, ALDH1B1, colorectal,
Immunohistochemical Expression of Cancer Stem Cell marker Aldehyde dehydrogenase 1B1 (ALDH1B1) in Colorectal Carcinoma
Background: Colorectal cancer (CRC) is the third most common cause of cancer-related death in the US. One out of four patients presenting with conventionally staged node negative disease (AJCC Stage I and II), and over 50% of patients with Stage III disease will develop local recurrence and/ or metastases. Across all stages, approximately 30% of patients will develop distant metastases. ... Read more

HOXB4 Immunoreactivity in Endometrial Tissues From Women With or Without Endometriosis
Endometriosis is a common disease characterized by the presence of ectopic endometrial tissue. Although the pathogenesis of endometriosis remains unclear, several factors have been implicated, including the dysregulation of homeobox (HOX) genes. Our objective was to investigate the localization and immunoreactivity of HOXB4 in endometrial tissues from women with or without endometriosis. We studied samples of eutopic endometrium (EE), endometriomas ... Read more