Dr.ramykamal

Ramy Kamal Amin Sayed

Lecturer - Lecturer of Veterinary Anatomy and Embryology

Faculty of Veterinary Medicine

Address: Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Sohag University

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Melatonin protects rats from radiotherapy-induced small intestine toxicity

2017 | Keywords melatonin, radiotherapy, small intestine toxicity,
Melatonin protects rats from radiotherapy-induced small intestine toxicity
Radiotherapy-induced gut toxicity is among the most prevalent dose-limiting toxicities following radiotherapy. Prevention of radiation enteropathy requires protection of the small intestine. However, despite the prevalence and burden of this pathology, there are currently no effective treatments for radiotherapy-induced gut toxicity, and this pathology remains unclear. The present study aimed to investigate the changes induced in the rat small intestine ... Read more

The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes

2017 | Keywords melatonin, Oxidative stress, exercise, Antioxidants, skeletal muscle, athletes,
The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes
Previous data showed that the administration of high doses of melatonin improved the circadian system in athletes. Here, we investigated in the same experimental paradigm whether the antioxidant properties of melatonin has also beneficial effects against exercise-induced oxidative stress and muscle damage in athletes. Twenty-four athletes were treated with 100 mg.day-1 of melatonin or placebo 30 min before bedtime during ... Read more

Oncostatic effect of melatonin in head and neck cancer: role of mitochondrial function

2017 | Keywords Mitochondrial function, cancer, melatonin,
Oncostatic effect of melatonin in head and neck cancer: role of mitochondrial function
Cancer cells have some special features that give them the ability to change and to resist different types of treatments. These changes are produced by modifications in the mitochondrial bioenergetics, that is, a switch in the metabolism. These advantages consist in the so-called Warburg effect. Cancer cells depend on glycolysis instead of oxidative phosphorylation to get the energy necessary to ... Read more

Macro and Microanatomical Studies on the Choanal Slit of Turkey (Meleagris gallopavo)

2017 | Keywords Choana, SEM, Palatine salivary glands, Palatine ridge, morphology,
Macro and Microanatomical Studies on the Choanal Slit of Turkey (Meleagris gallopavo)
This work was carried out to describe the morphological characteristics of the choanal slit of the turkey through gross, light, and scanning electron microscopy. The choanal slit measures 27.62 mm long, and constitutes 38.30 % of the total length of the palate. The edges of the narrow part of the choanal slit is smooth rostrally but slightly thickened caudally due ... Read more

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome

2017 | Keywords Blood pressure, COX, glutathione, mitochondrial disease, SQR,
CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome
Coenzyme Q (CoQ) is a key component of the mitochondrial respiratory chain, but it also has several other functions in the cellular metabolism. One of them is to function as an electron carrier in the reaction catalyzed by sulfide:quinone oxidoreductase (SQR), which catalyzes the first reaction in the hydrogen sulfide oxidation pathway. Therefore, SQR may be affected by CoQ deficiency. ... Read more

Gross Anatomical, Light and Scanning Electron Microscopic Studies on the Pharyngeal Roof of Turkey (Meleagris gallopavo): Comparative Study

2016 | Keywords Oropharynx, Pharyngeal folds, SEM, Sphenopterygoid salivary gland,
Gross Anatomical, Light and Scanning Electron Microscopic Studies on the Pharyngeal Roof of Turkey (Meleagris gallopavo): Comparative Study
pharyngeal roof using light and scanning electron microscopy. Studied parts from the roof of the turkey's pharynx were processed and stained by convential stains to illustrate the mucosa, salivary glands, and connective tissue infiltration. Also, Scanning electron investigations were applied on pharyngeal papillae and pharyngeoseophageal junction. Grossly, the pharyngeal roof was shown to constitute about 12.27% of the oropharyngeal roof ... Read more

NLRP3 inflammasome affects mitochondrial morphology in skeletal muscle of mice

2016 | Keywords NLRP3 inflammasome, Muscle fibers, Mitochondria, CSA,
NLRP3 inflammasome affects mitochondrial morphology in skeletal muscle of mice
NLRP3 inflammasome seems to affect negatively skeletal muscle and mitochondria morphology. NLRP3 is associated with mitochondrial dysfunction and damage after its activation by inflammatory signals. Finally, these changes may reflect loss of efficacy of the skeletal muscle strength. Read more

Aging and Sarcopenia. Role of the innate immunity and melatonin therapy

2016 | Keywords Aging, Sarcopenia, Inflammaging, Innate immunity, melatonin,
Aging and Sarcopenia. Role of the innate immunity and melatonin therapy
La inflamación asociada al envejecimiento es un tipo de inflamación crónica, sistémica y asintomática que aparece como resultado de un aumento de la respuesta inmune innata con la edad. Los estímulos que dan lugar a este tipo de inflamación convergen en la activación de las vías moleculares de la inmunidad innata NF-kB y el inflamasoma NLRP3. La inflamación asociada al ... Read more

Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice

2016 | Keywords Sarcopenia, Aging, CSA, Type II muscle fibers, Mitochondria,
Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice
The gastrocnemiusmuscle (GM) of young (3months) and aged (12 months) femalewild-type C57/BL6 micewas examined by light and electron microscopy, looking for the presence of structural changes at early stage of the aging process.Morphometrical parameters including body and gastrocnemius weights, number and type ofmuscle fibers, cross section area (CSA), perimeter, and Feret's diameter of single muscle fiber,were measured.Moreover, lengths of the ... Read more

Palate of Turkey (Meleagris gallopavo): Gross Anatomical, Light and Scanning Electron Microscopical Study

2016 | Keywords Turkey, SEM, Palate , Oropharynx, Meleagris gallopavo,
Palate of Turkey (Meleagris gallopavo): Gross Anatomical, Light and Scanning Electron Microscopical Study
This investigation aimed to determine the morphological characteristics of the palate of bronze black turkey by gross anatomy, light and scanning electron microscopy. The oral roof (palate) constitutes 87.73% of the oropharyngeal roof length, comprising two parts; rostral and caudal. The rostral part is characterized by the presence of median palatine ridge, rostral and caudal lateral palatine ridges, narrow part ... Read more