eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

23

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Epidemiological features of crystal induced arthritis: A hospital-based study in Upper Egypt
Objective: To evaluate the epidemiological features and risk factors for crystal induced arthritis in patients presented to Rheumatology Clinic, Sohag University, Upper Egypt. Patients and Methods: A hospital based study was carried on 30 patients; 17 male and 13 female attending the outpatient Clinic of Rheumatology and Rehabilitation Department of Sohag University Hospital in the period from April 2011 to ... Read more

2012 | Keywords Reed Sternberg-Like Cell,
Hodgkin Reed Sternberg-Like Cells in Reactive and Immunosuppression-Associated Lymphoproliferative Disorders
Many non-Hodgkin's lymphomas (NHLs), reactive processes and some leukemias may contain large transformed lymphocytes that resemble in appearance, and perhaps in immunohistochemical features, Hodgkin Reed Sternberg (HRS) cell or Lymphocyte Predominant cell (LP); the essential landmark for diagnosis of Hodgkin's lymphoma (HL) (Rosai, 2004). Differentiation from mimickers is important because current multimodality treatment protocols achieve cure in over 90% of ... Read more

2012 | Keywords Soft Tissue Sarcoma,
Prognostic Variables in Soft Tissue Sarcoma
Background/aims: Soft tissue sarcomas form a heterogeneous group of mesenchymal neoplasm that can arise almost anywhere in the body. Treatment and prognosis are interdependent factors. Accurate determination of prognosis is critical in order to guide therapeutic decisions. This study aimed to analyze some prognostic factors in soft tissue sarcoma. Methods used to collect evidences: Visiting sites on the internet to ... Read more

2012 | Keywords Endometrium, B-Catenin,
B-Catenin expression in benign and neoplastic endometrium
Background: Endometrial carcinoma is one of the most common malignancies of female genital tract. Well differentiated endometrioid carcinoma is histologically similar to complex atypical endometrial hyperplasia and sometimes it is difficult to differentiate between them. We hypothesis that expression of the oncogene B-Catenin may vary in different endometrial lesions and the difference in its expression may be of value to ... Read more

2012 | Keywords endometr, B-Catenin, PCNA, TEN,
The value of PTEN, PCNA and B-Catenin to differentiate between endometrial hyperplasia and endometrial adenocarcinoma
Endometrial carcinoma is one of the most common malignancies of female genital tract. Well differentiated endometrioid carcinoma is histologically similar to complex atypical endometrial hyperplasia and sometimes it is difficult to differentiate between them. We hypothesis that the use of PTEN the tumor suppressor gene, PCNA a marker of proliferation and B-Catenin oncogene may be of value to differentiate well ... Read more

2012 | Keywords IL-8, COX-2,
Expression of Cyclooxygenase-2 (COX-2) and Interleukin-8 (IL-8) in H. pylori Gastritis; A Study on Diagnostic Methods and Pathological Effects of H. pylori Infection in Dyspeptic Patients
_BACKGROUND__ H. pylori_ infection causes diverse clinical outcomes, including dyspepsia, peptic ulceration, gastric carcinoma and mucosa associated lymphoid tissue (MALT) lymphoma. Up-regulation of COX-2 has been observed in _H. pylori_ gastritis in response to inflammatory cytokines. IL-8 is a major activator for neutrophils which contribute to mucosal damage in _H. pylori_ infected patients. A wide-spread use of non-invasive simple diagnostic ... Read more

2012 | Keywords FNAC, Breast Lumps,
Validity of Fine Needle Aspiration Cytology (FNAC) in Diagnosis of Breast Lumps in Upper Egypt
INTRODUCTION: A palpable breast lump is a common diagnostic problem both to the general practitioner and to the surgeon, which needs rapid definitive diagnosis at the busy Outpatient Clinic. Fine needle aspiration cytology (FNAC) has become the first choice for diagnosis after initial clinical evaluation. AIM OF THE WORK: This study was designed to investigate the validity of FNAC in ... Read more

Angiogenesis and its Correlation to some Clinico-pathological Parameters in Infiltrating Duct Carcinoma of the Breast
BACKGROUND: Breast cancer represents a group of tumors with a tremendous heterogeneity in its behavior, outcome, and response to therapy. Angiogenesis is an important key step in tumor progression. Microvascular density (MVD), a surrogate marker of angiogenesis can be assessed by CD31 immunostaining. THIS STUDY AIMS TO evaluate CD31 and p53 expressions in breast cancer, and to determine their correlations ... Read more

Immunohistochemical P53 Expression in Breast Carcinoma with Correlation to Clinico-Pathological Parameters
Breast cancer has emerged as a grave danger in the last 50 years. It represented 35.1% of total cancer in women in Egypt National Cancer Institute (NCI) series. Changes in cell loss factor could have a major impact on tumor growth or regression. A large percentage of cell loss from tumors was due to apoptosis. P53 is a tumor suppressor ... Read more

Evaluation of some Histochemical and Immunohistochemical Criteria of Round Cell Tumors of Bone (RCTB)
BACKGROUND/AIMS: Differential diagnosis of RCTB; Ewing sarcoma, small cell osteosarcoma, mesenchymal chondrosarcoma, osteoblastoma, chondroblastom, primary bone lymphoma and multiple myeloma is still challenging. Given the significant differences in treatment, accurate diagnosis is imperative. This study aimed to evaluate some histochemical and immunohistochemical criteria of RCTB. SUBJECTS AND METHODS: PAS, CD99, CD138, osteocalcin, and LCA were evaluated in 113 cases of ... Read more