Objective: To evaluate the efficacy of chitosan- methylene blue (MB) hydrogel mediated photodynamic therapy in the treatment of freckles. Patients and methods: Thirty four patients complaining from freckles were recruited in this Prospective, split-face controlled study. Pregnant women, patients with photosensitive dermatosis, other contraindications for phototherapy and use of topical or systemic retinoid treatment in the past 6 months were ... Read more