Expression of p53, bcl-2, bax and bcl-xl in breast ductal carcinoma in situ (DCIS) .
Background: DCIS is a malignant proliferation of mammary ductal epithelial cells without invasion beyond the basement membrane. Bcl-2, bax, bcl-xl and p53 are implicated in regulation of apoptosis. This study aimed to clarify the rokle of these gene products in DCIS. Patients and methods: Immunohistochemical staining of 13 cases of DCIS with bcl-2, bax, bcl-xl and p53 was performed. Results: ... Read more