ahmedabudief

Prof. Ahmed Mohamed Abu-Dief

Professor - Professor of Physical and Inorganic Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

342

Like

Bio-Inorganic Chemistry

2024-04-23 11:03:31 |

List of Topics

Planned Contact hours

Actual Contact hours

Reason for Variations if there is a difference of more than 25% of the hours planned

1.     Introduction:

 

1.1  Amino acids, peptides and proteins

1.2  Proteins, enzymes, cofactors

1.3  Classification of elements according to their action in biological system,

1.4  Fundamentals of Coordination Chemistry

1.5  Physical Methods for Bioinorganic Chemistry  

4

4

 

2.     Transport and Storage of Metal Ions

 

2.1  Transport and Storage of iron within organisms

2.2  Transferrin, Lactoferrin and Ferritin

2.3  Iron from the environment

2.4  Siderophores and ferrioxamine

4

4

 

3.     Oxygen metabolism

 

3.1  Dioxygen carriers:

3.1.1      Haemoglobin and myoglobin,

3.1.2      Hemerythrin,

3.1.3       Hemocyanin

3.2  Oxygen-activating enzymes (Cytochrome P-450)

3.3  Cytochrome c oxidase (Cytochrome c oxidase)

3.4  Enzymes that get rid of superoxide (Superoxide dismutase, Superoxide reductase)

6

6

 

4.     Zn2+ ion:

 

4.1  carbonic anhydrase

4.2  carboxypeptidase

4.3  carboxypeptidase

4.4  Cobalt for Zn ion substitution

4

4

 

 

 

 

 

5.     Biological redox processes

 

5.1  Blue copper proteins

5.2  The mitochondrial electron transfer chain

5.3  Iron sulfur proteins

5.4  Cytochromes

 

6

6

 

6.     Metals and Health:

 

6.1  Metal-based drugs

6.1.1      Cis-platin, carboplatin, platinum anti-cancer drugs

6.1.2      Gadolinium MRI contrast agents,

6.2  Metal toxicity

6.2.1      Iron overload,

6.2.2      mercuric ion reductase,

6.2.3       lead

6.2.4      porphobilinogen synthase

 

4

4

 


2024-04-23 11:16:16 | Bio-Inorganic Chemistry
Choose the correct answer
1-Which biologically active species control important cellular process such as oxidation/reduction, hydrolysis, and methyl group transfer? metalloproteins free proteins free metal ions 2-BioInorganic chemistry is the study of -------- utilized in biology Inorganic elements Physical chemistry ... Read more

2024-05-13 22:02:50 | Bio-Inorganic Chemistry
Assay
How the trasferrin works?... Read more

2024-05-13 22:27:37 | Bio-Inorganic Chemistry
Trace elements
Write about the importance of trace elemnts in body?... Read more

2024-05-13 22:49:44 | Bio-Inorganic Chemistry
Syntheis
Write about the exprimental method for synthesis of Porphrin?... Read more