List of Topics |
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1. Introduction:
1.1 Amino acids, peptides and proteins 1.2 Proteins, enzymes, cofactors 1.3 Classification of elements according to their action in biological system, 1.4 Fundamentals of Coordination Chemistry 1.5 Physical Methods for Bioinorganic Chemistry |
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2. Transport and Storage of Metal Ions
2.1 Transport and Storage of iron within organisms 2.2 Transferrin, Lactoferrin and Ferritin 2.3 Iron from the environment 2.4 Siderophores and ferrioxamine |
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3. Oxygen metabolism
3.1 Dioxygen carriers: 3.1.1 Haemoglobin and myoglobin, 3.1.2 Hemerythrin, 3.1.3 Hemocyanin 3.2 Oxygen-activating enzymes (Cytochrome P-450) 3.3 Cytochrome c oxidase (Cytochrome c oxidase) 3.4 Enzymes that get rid of superoxide (Superoxide dismutase, Superoxide reductase) |
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4. Zn2+ ion:
4.1 carbonic anhydrase 4.2 carboxypeptidase 4.3 carboxypeptidase 4.4 Cobalt for Zn ion substitution |
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5. Biological redox processes
5.1 Blue copper proteins 5.2 The mitochondrial electron transfer chain 5.3 Iron sulfur proteins 5.4 Cytochromes
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6. Metals and Health:
6.1 Metal-based drugs 6.1.1 Cis-platin, carboplatin, platinum anti-cancer drugs 6.1.2 Gadolinium MRI contrast agents, 6.2 Metal toxicity 6.2.1 Iron overload, 6.2.2 mercuric ion reductase, 6.2.3 lead 6.2.4 porphobilinogen synthase
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