omaima.abdelatef

Omyma Abd Elaziz Abd El-Latif Abd Allah

Professor - Staff member

Faculty of science

Address: Chemistry Department - Faculty of Science - Sohag University

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Omyma Abd Elaziz Abd El-latif Abd Allah, a Professor of Organic Chemistry, Chemistry Department, Faculty of Science, Sohag University. I awarded my M.Sc. in Organic Chemistry (1989) and my Ph.D. in Organic Chemistry (1995). My research is the Synthetic Organic Chemistry, Medicinal Chemistry and Organoclays Synthesis as shown in the given list below. Also, I have a history of several years of teaching for college students and various trends in different universities.  

I have very well experience in the following fields:

1-Synthetic organic chemistry

2-Synthesis of medicinal molecules

 3-Organoclays synthesis

4- Green chemistry  

5- Multi-component reactions

6- Molecular modeling and structure

7- Characterization of organic compounds

8- Phase Transphere Catalysis Technique 

9- Spectral analyses (UV, IR, NMR and M.S).

10- Reaction mechanism

11- Chromatography 

12- Solutions of chemical problems related to the local environments.

 

 


2018-10-18 12:59:44 | Keywords polyhydroquinolines, pharmaceutical drugs, 3-cyclohexanedione, 1,
An Efficient One Pot Three-Components Synthesis of Some New Polyhydroquinolines via Enaminone Intermediates;
For a wide spectrum of pharmacological effects of polyhydroquinolines, this study introduces a developed safe, simple, higher yields and fast method for the synthesis of some new hexahydroquinoline derivatives using one-pot three-component cyclocondensation reaction, via the reaction of 1,3-cyclohexanedione with primary amine and arylidinemalononitrile or salicylaldehyde derivatives. The prepared compounds were reacted with different reagents as N,N-dimethylformamide dimethylacetal, acetic anhydride, ... Read more

2018-10-18 13:13:18 | Keywords pyrimidonapht, acrylonitrile, benzylidenemal, naphthyridine, ,
Synthesis of Some New 1,8-Naphthyridines From N-(7-Chloro-5-Methyl-1,8-Naphthyridine-2-yl) Acetamide and 7-Amino-2-Chloro-4-Methyl-1,8-Naphthyridine
The first parent compound N-(7-chloro-5-methyl-1,8-naphthyridine-2- yl)acetamide was reacted with both of ethyl thioglycolate forming ethyl [{7-(acetylamino)-4-methyl-1,8-naphthyridine-2yl} sulfanyl] acetate and ethyl[(-7-amino-4-methyl-1,8- naphthyridine-2yl) sulfanyl] acetate and with thioacetamide to afford N-[5-methyl-7- sulfanyl-1,8-naphthyridine-2-yl] acetamide. The last product was used as an intermediate for the synthesis of different novel mercapto derivatives. The second parent compound 7- amino-2-chloro-4-methyl-1,8-naphthyridine was reacted with several active organic compound ... Read more

SYNTHESIS, STRUCTURAL STABILITY CALCULATION, AND ANTIBACTERIAL EVALUATION OF NOVEL 3,5-DIPHENYLCYCLOHEX-2-EN-1-ONE DERIVATIVES
Starting with 3,5-diphenylcyclohex-2-en-1-one, 3,5-diphenylcyclohex-2-en-1-semicarbazone,1-chloro-3,5-diphenylcyclohex-2-en-2-carbaldehyde,and3,5-diphenylcyclohex2-en-1-hydrazone were synthesized via the reactions with semicarbazide hydrochloride,POCl3= dimethylformamide, and hydrazine hydrate, respectively. These products were used as key intermediates for the preparation of novel series of tetrahydrobenzothiadiazol-1-oxide, indazole, benzo-thiazepines, pentahydroxyhexylidene and N-thiazines. Some of these derivatives exhibit high antibacterial activityagainst Gram-positive bacteria. Read more

2018-10-22 12:12:50 | Keywords 8] naphthyridine, anti-inflammatory, [1, PTC, thiocurcumin, Curcumin,
Synthesis and Evaluation of Some Novel Curcumin Derivatives as Anti-inflammatory Agents
Starting with curcumin different pyrane, N-phenyl-1,3-thiazolidin and thiocurcumin derivatives were synthesized. 4-Oxo-3-phenyl1,3-thiazolidin derivative was reacted with different organic reagents examply, benzaldehyde, triethylorthoformate and hydrazine hydrate to form new series of 5-benzylidine-4-oxo-3-phenyl-1,3-thiazolidin, 5-ethoxymethylene-4-oxo-3-phenyl-1,3-thiazolidin and [1,8] naphthyridine derivatives. Some of these derivatives were evaluated as anti- inflammatory agents. All compounds have been characterized by spectral analyses. Read more

2018-10-22 12:18:00 | Keywords Naproxen; anti-inflammatory;, NSAID’s.,
Synthesis of New Potential Chemotherapeutic Agents Incorporating Naproxen Sub-Structure.
A series of potential biologically active compounds have been synthesized through the derivatization of carboxyl group in Naproxen core structure involving the conversion the Naproxen to its methyl ester then to the acid hydrazide. The acid hydrazide of Naproxen was incorporated with hydrazones, diamide linkage, oxadiazole, pyrazolone, triazole, quinazoline and indole containing motifs. The targeted compounds have been achieved in ... Read more