Dr. Ahmed Mohamed Abu-Dief

Professor - Professor of Physical and Inorganic Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street


2022 | Keywords SARS-CoV-2,
Using Safe Calculated Low Power of Electrons to Cut, Analyze and Exterminate the Outer and Inner Biological Elements of SARS-CoV-2, MERS-CoV-2 and Influenza viruses in Vitro
Background: The treatment of pneumonia viruses with antiviral drugs produced mild to severe side effects until the immune system worked against the invaded virus. Objective: Therefore, it is crucial to develop an efficient alternative therapy with lower side effects against infection of pneumonia viruses. Methods: We hereby designated a novel device termed a a Life Restoration Device (LRD to produce ... Read more

2022 | Keywords DNA interaction,
Synthesis, Structural elucidation, DFT calculation, Biological studies and DNA Interaction of Some Aryl hydrazone Cr3+, Fe3+, and Cu2+ Chelates
The current research focuses on the treatment of Cr(III), Fe(III) and Cu(II) metal ions with aryl hydrazone ligand named (E)-4-(((diphenylmethylene)hydrazono)methyl)benzene-1,3-diol (DPHB) to afford four novel solid complexes with high yields. Different characterization approaches, including infrared, UV-visible, and NMR spectroscopies, elemental analyses, and thermal gravimetric analysis (TGA), revealed that all mononuclear crystalline metal chelates with good thermal stability had a six-coordination ... Read more

Tailoring of Novel Azithromycin-Loaded Zinc Oxide Nanoparticles for Wound Healing
Skin is the largest mechanical barrier against invading pathogens. Following skin injury, the healing process immediately starts to regenerate the damaged tissues and to avoid complications that usually include colonization by pathogenic bacteria, leading to fever and sepsis, which further impairs and complicates the healing process. So, there is an urgent need to develop a novel pharmaceutical material that promotes ... Read more

2022 | Keywords (AgNPs,
Green Biogenic Synthesis of Silver Nanoparticles Using Aqueous Extract of Moringa Oleifera: Access to a Powerful Antimicrobial, Anticancer, Pesticidal and Catalytic Agents
In this study, we look into the biogenic synthesis of (AgNPs) utilizing a simple and environmentally friendly method based on an aqueous extract of _Moringa Oleifera_ (MO). The synthesized MOAgNPs were characterized using a UV–Visible spectrophotometry, X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectra and TEM image which confirmed the spherical shape of MOAgNPs with particle size range of 5–50 ... Read more

2021 | Keywords
Opinion on The Development of  Nanotechnology for Treatment  of Coronaviruses
nparalleled public health danger. The disease was discovered in late December 2019 in Wuhan, Hubei Province, China, with an exceptionally high rate of spread. The virus that causes COVID-19 (SARS-CoV-2), has infected over 118 million people and caused 2.5 million deaths in 216 countries, with the numbers continuing to rise. There are currently no officially licensed vaccines or antiviral drugs ... Read more

2021 | Keywords Antimicrobial, anti-cancer,
Temperature and salt effects of the kinetic reactions of substituted 2-pyridylmethylene-8-quinolyl iron (II) complexes as antimicrobial, anti-cancer and antioxidant agents with Cyanide ions
Kinetics of substitution reaction of three high spin pyridylmethylene-8-quinolyl iron (II) complexes by CN- ions are studied spectophotometrically in various ratios of aqueous-methanol binary mixtures at 298 ± 0.2 K. Kinetics of the substitution reaction follow the rate law (k2[CN−][complex])on applying of the conditions of the pseudo-first-order. Reactivity of the reaction was investigated in terms of organic ligand moiety and ... Read more

Tailoring, structural inspection of novel oxy and non-oxy metal-imine chelates for DNA interaction, pharmaceutical and molecular docking studies
A green synthetic pathway for two mononuclear M(II)-complexes (M = Ni2+ as a non-oxy-metal ion and ZrO2+ as an oxy-metal ion, NiLig and ZrOLig, respectively) of an imino-naphthalenol sodium sulfonate ligand (H2Lig) was followed. Using various physico-chemical tools, their chemical compositions were elucidated. The material-studio package was applied to confirm the structures of NiLig and ZrOLig _via_ the DFT method. ... Read more

2021 | Keywords Colorectal cancer,
Novel Green Biosynthesis of 5-Fluorouracil Chromium Nanoparticles Using Harpullia Pendula Extract for Treatment of Colorectal Cancer
Colorectal cancer (CRC) is the third major cause of morbidity and mortality worldwide. Hence, many strategies and approaches have been widely developed for cancer treatment. This work prepared and evaluated the antitumor activity of 5-Flurouracil (5-Fu) loaded chromium nanoparticles (5-FuCrNPs). The green biosynthesis approach using Harpullia (H) pendula aqueous extract was conducted for CrNPs preparation that was further loaded with ... Read more

Synthesis and structural elucidation for new pyrano thiazole complexes: Biological screening and effects on DNA through in-vitro and in-silico approaches
Novel bioactive complexes were prepared from Cu(II), Fe(III) and Pd(II) ions with pyrano thiazole derivative (PTP) [2-amino-6-oxo-3-(piperidinylamidino)-4-phenyl-6,7-dihydro-pyrano[2,3-d]-5,7-thiazol]. CHN, FT-IR, UV–Vis, 1H NMR, 13C NMR, molar conductance and TGA results have been used to determine the chemical formulae of new compounds. Accordingly, the octahedral geometry was proposed for the complexes except PTPPd complex (square-planer). The ligand acts as a neutral bidentate ... Read more

2021 | Keywords Manfort, infertility, sperm qu,
Manfort: A dietary supplement for semen parameters quality improvement in low sperm count and azoospermia patients
BACKGROUND: The production of healthy sperms from testicular tissues which able to successfully fertilize the mature egg is the main target of the recent studies. Recently dietary supplements composed from multi-natural products extracted from medicinal herbs are used for sperm parameters improvement compared with chemically-based synthesized drugs. This traditional method of treatment is safe, effective and low costed compared with ... Read more