Alopecia areata is the most prevalent autoimmune disorder which causes non-scarring hair loss. It may increase the anxiety of patients and increase their chances of developing psychological and psychiatric disorders. There are two proposed theories for the pathogenesis of alopecia areata. The most evidence-based hypothesis is an autoimmune reaction caused by the collapse of hair follicle immune privilege, Immune privilege ... Read more

Vitiligo is an acquired skin disorder that is characterized by a gradual loss of skin pigmentation when melanocytes, the skin's pigment-producing cellsis lost. Pathogenicmechanisms are not well understood. Genetic, abnormal biochemical pathways, autoimmune, melanocyte adhesion deficits and nervous system imbalances are among the pathogenic triggers. Vitiligo lesions have also been shown to have macrophage infiltration.Macrophagemigration inhibitory factor (MIF) is a ... Read more

Abstract: Alopecia areata is a common cause of nonscarring alopecia, with patchy, confluent, or diffuse patterns, involving mainly the scalp and other hairy areas of the body. It's considered a therapeutic challenge due to prognosis, unpredictable course, and variable efficacy of available therapies. Several studies have evaluated the efficacy of cryotherapy in the treatment of alopecia areata with varying success ... Read more

Purpose: Psoriasis vulgaris, one of the most prevalent chronic inflammatory skin diseases, is associated with metabolic syndrome (MetS). Autophagy, an intracellular degradation system is essential for cell survival and differentiation, and its dysfunction may contribute to metabolic diseases. A cross-sectional study was conducted on 38 psoriasis vulgaris patients and 16 healthy control subjects to 1) Assess immunohistochemical (IHC) expression of ... Read more

INTRODUCTION AND OBJECTIVE: 10 -20% of infertile men suffer from azoospermia of which up to 60% is presumed to have a non-obstructive (NOA) cause. Whilst there have been studies showing improved sperm retrieval rates (SSR) in men with NOA and low Testosterone by treatment with clomiphene, Human chorionic gonadotropin (hCG) and human menopausal gonadotropin (hMG), no treatment protocols have consistently ... Read more

Purpose: Psoriasis vulgaris, one of the most prevalent chronic inflammatory skin diseases, is associated with metabolic syndrome (MetS). Autophagy, an intracellular degradation system is essential for cell survival and differentiation, and its dysfunction may contribute to metabolic diseases. A cross-sectional study was conducted on 38 psoriasis vulgaris patients and 16 healthy control subjects to 1) Assess immunohistochemical (IHC) expression of ... Read more

Diagnosis of onychomycosis requires microbiological studies, which are time-consuming. Dermoscopy is non invasive, easy and coastless method. To evaluate the diagnostic role of dermoscopy in onychomycosis and comparing its findings with microbiological results. Eighty patients with onychomycosis and 40 controls were studied for nail dermoscopic finding, and microbiological examinations in the form of microscopic examination by 20% KOH, Sabouraud dextrose ... Read more

AIM OF THE WORK : To evaluate the efficacy of Erbium-YAG laser alone and in combination of platelet-rich plasma (PRP) in atrophic post acne scars. PATIENTS AND METHODS: This study was a prospective non randomized clinical trial. 50 patients were included in this study, examined and divided into two groups. Group A included 25 patients were subjected to 6 Erbium-YAG ... Read more

AIM OF THE WORK: To evaluate the effect of human chorionic gonadotropin and antioxidants on semen parameters after varicocelectomy in infertile patients. PATIENTS AND METHODS: This is a randomized prospective clinical trial. This study included 60 varicocele infertile patient with oligoasthenoteratozoospermia (OAT) undergo varicocelectomy. Patients were randomly divided into four groups : Patients in group (A) were treated with HCG ... Read more

Summary Background: Despite the wide therapeutic options available for the treatment of me‐ lasma, including many active topical medications, technologies with lights and peel‐ ings, clinical control of this disorder is extremely challenging. Objectives: To evaluate the effect of microneedling with topical vitamin C in the treatment of melasma. Methods: Thirty female patients with melasma received six sessions of micronee‐ ... Read more