Human scalp skin and hair follicles express neurotophin-3 (NT-3) and its high affinity receptor tyrosine kinase C (TrKC) and show hair cycle-dependent expression alterations.
Objective: neurotrophin - 3 (NT-3) and its high affinityreceptor tyrosine kinase C (TrK C) are essential for nervous system development. Recently, it has been shown thatthese members of the neurotrophin family are also involved in murine hair morhoenesis and ycling. However, their role in human hair follicle biology remains to be elucidated. As a first step towards this end, we ... Read more