ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Kinetic study of the hydroxide ion attack on and DNA interaction with high spin iron(II) Schiff base amino acid chelates baering ONO donors
Kinetic study of some novel high spin Fe(II) complexes of Schiff base ligands derived from 5-bromsalicyaldehyde and amino acids with the OH− ion and DNA has been carried out. Based on the kinetic data, the rate law and a plausible mechanism were proposed. Kinetic data of the base catalyzed hydrolysis imply pseudo first-order double stage process due to the presence ... Read more

Reactivity Trends and Kinetic Inspection of Hydroxide Ion Attack and DNA Interaction on Some Pharmacologically Active Agents of Fe(II)  Complexes at Different Temperatures
The reactivity of few novel high‐spin Fe(II) complexes of Schiff base ligands derived from 2‐hydroxynaphthaldehyde and some variety of amino acids with the OH− ion has been examined in an aqueous mixture at the temperature range from 10 to 40°C. Based on the kinetic investigations, the rate law and a plausible mechanism were proposed and discussed. The general rate equation ... Read more

Kinetic study and reactivity trends of hydroxide ion attack on some chromen-2-one laser dyes in binary water-methanol and water-acetone mixtures
The kinetics of base-catalyzed hydrolysis of 7-dimethylamino-4-methyl-2_H_-chromen-2-one (DMAC) and 7-diethylamino-4-methyl-2_H_-chromen-2-one (DEAC) in binary water-methanol and water-acetone mixtures were studied in the temperature range from 288 to 313 K. The activation and thermodynamic parameters of these reactions were evaluated and discussed. The change in the activation energy in going from water to aqueous methanol and aqueous acetone was estimated from the ... Read more

Metal based pharmacologically active agents: Synthesis, structural characterization, molecular modeling, CT-DNA binding studies and in vitro antimicrobial screening of iron(II) chelates
In recent years, great interest has been focused on Fe(II) Schiff base amino acid complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 5-bromosalicylaldehyde (bs) and α-amino acids (l-alanine (ala), l-phenylalanine (phala), l-aspartic acid (aspa), l-histidine (his) and l-arginine (arg)). The ... Read more

Kinetics of Alkaline Hydrolysis and DNA Interaction of Iron Complexes
Air and moisture stable coordination compounds of some first transition metals such as Cr (III), VO (II), Ni(II) and Mn(II) with newly designed tri- and tetra-dentate imine ligands (HNAP, HNPN and ESPN) were synthesized. Tridentate imine ligands (HNAP, ESAP) were synthesized by reacting 2-hydroxynapthaldehyde (HN) with 2-aminophenol (AP), whereas tetra-dentate imine ligands (HNPN and ESPN) were prepared by reacting 2-hydroxy-1-napthaldehyde ... Read more

Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes
New Fe(II) Schiff base amino acid complexes derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized by elemental analysis, IR, electronic spectra, and conductance measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. The investigated Schiff bases exhibited tridentate coordination mode with the general formulae [Fe(HL)2]·nH2O for ... Read more

Kinetic investigation of hydroxide ion attack at high spin Fe(II) bromosalicylidine chelates with amino acids in binary aqueous solvents: Initial and transition state analysis
We have investigated the kinetics of hydroxide ion attack at iron(II) chelates with 5-bromosalicylidene derivatives of amino acids (alanine, phenylalanine, aspartic acid, histidine, and arginine) in binary aqueous mixed solvents at 298 K. The observed reactivity trends are discussed in connection with the complexes hydrophobicity/hydrophilicity, transfer chemical potentials of hydroxide ion and the complex, and the solvent effects. Read more

Novel sandwich triple-decker dinuclear NdIII-(bis-N,N′-p-bromo-salicylideneamine-1,2-diaminobenzene) complex
In the search of new multifunctional molecular materials, the present paper introduces the work performed with the Salen-type Schiff base: bis-_N_,_N_′-_p_-bromo-salicylideneamine-1,2-diaminobenzene (H2bsph), to attain novel coordination complexes containing lanthanides centers (LnIII). So far, our studies have shown that the combination in acetone of the well-known H2bsph ligand, a base and NdIII(NO3)3·6H2O, results in a yellow solid which crystalline forms has ... Read more

Design, characterization, teratogenicity testing, antibacterial, antifungal and DNA interaction of few high spin Fe(II) Schiff base amino acid complexes
In this study, new Fe(II) Schiff base amino acid chelates derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized via elemental, thermogravimetric analysis, molar conductance, IR, electronic, mass spectra and magnetic moment measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. Correlation of all spectroscopic data suggested ... Read more

Design, Physicochemical Studies and DNA Interaction of Some Complexes
In recent years, great interest has been focused on Fe(II) Schiff bases amino acids complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 2-hydroxy-1-naphthaldehyde and 5-bromosalicylaldehyde (bs) with α-amino acids ((L-alanine (ala), L-phenylalanine (phala), L-aspartic acid (aspa), L-histidine (his) and L-arginine ... Read more